Antimicrobial consumption and antimicrobial resistance:a snapshot of an Italian neuromuscular rehabilitation center

Giuseppina Barberi, Maria Cristina De Cola, De Cola Dell'Utri, Sara Melardi, Bernardo Alagna, Placido Bramanti, Antonio Cascio

Research output: Contribution to journalArticle

Abstract

The paper presents a snapshot of the incidence of antimicrobial-resistant microorganisms and antimicrobial consumption in an Italian rehabilitation center over a two-year period (2014-2015). Data on microorganism identification and antimicrobial susceptibility testing were obtained from the diagnostic laboratory of the hospital. A set of indicators was assessed, including the incidence density of resistant isolates per 1000 patient-days (IDRI). Data on antimicrobial consumption, semi-annually, obtained from the hospital pharmacy, were expressed as Defined Daily Dose (DDD) per 1000 patient-days. The most frequently isolated microorganism was Klebsiella pneumoniae (19.3%), and a significant increase in piperacillin/tazobactam- resistant K. pneumoniae (p=0.04) was observed. Among all antimicrobials used, carbapenems were the most prescribed antibiotic class (31%).

Original languageEnglish
Pages (from-to)119-129
Number of pages11
JournalNew Microbiologica
Volume40
Issue number2
Publication statusPublished - Apr 2017

Keywords

  • Anti-Bacterial Agents
  • Bacteria
  • Catheters
  • Drug Resistance, Bacterial
  • Drug Utilization
  • Intubation, Gastrointestinal
  • Italy
  • Neuromuscular Diseases
  • Rehabilitation Centers
  • Risk Factors
  • Journal Article

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    Barberi, G., De Cola, M. C., Dell'Utri, D. C., Melardi, S., Alagna, B., Bramanti, P., & Cascio, A. (2017). Antimicrobial consumption and antimicrobial resistance:a snapshot of an Italian neuromuscular rehabilitation center. New Microbiologica, 40(2), 119-129.