Antimicrobial consumption and antimicrobial resistance:a snapshot of an Italian neuromuscular rehabilitation center

Giuseppina Barberi, Maria Cristina De Cola, De Cola Dell'Utri, Sara Melardi, Bernardo Alagna, Placido Bramanti, Antonio Cascio

Research output: Contribution to journalArticle

Abstract

The paper presents a snapshot of the incidence of antimicrobial-resistant microorganisms and antimicrobial consumption in an Italian rehabilitation center over a two-year period (2014-2015). Data on microorganism identification and antimicrobial susceptibility testing were obtained from the diagnostic laboratory of the hospital. A set of indicators was assessed, including the incidence density of resistant isolates per 1000 patient-days (IDRI). Data on antimicrobial consumption, semi-annually, obtained from the hospital pharmacy, were expressed as Defined Daily Dose (DDD) per 1000 patient-days. The most frequently isolated microorganism was Klebsiella pneumoniae (19.3%), and a significant increase in piperacillin/tazobactam- resistant K. pneumoniae (p=0.04) was observed. Among all antimicrobials used, carbapenems were the most prescribed antibiotic class (31%).

Original languageEnglish
Pages (from-to)119-129
Number of pages11
JournalNew Microbiologica
Volume40
Issue number2
Publication statusPublished - Apr 2017

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Rehabilitation Centers
Klebsiella pneumoniae
Hospital Laboratories
Carbapenems
Incidence
Anti-Bacterial Agents
tazobactam drug combination piperacillin

Keywords

  • Anti-Bacterial Agents
  • Bacteria
  • Catheters
  • Drug Resistance, Bacterial
  • Drug Utilization
  • Intubation, Gastrointestinal
  • Italy
  • Neuromuscular Diseases
  • Rehabilitation Centers
  • Risk Factors
  • Journal Article

Cite this

Barberi, G., De Cola, M. C., Dell'Utri, D. C., Melardi, S., Alagna, B., Bramanti, P., & Cascio, A. (2017). Antimicrobial consumption and antimicrobial resistance:a snapshot of an Italian neuromuscular rehabilitation center. New Microbiologica, 40(2), 119-129.

Antimicrobial consumption and antimicrobial resistance:a snapshot of an Italian neuromuscular rehabilitation center. / Barberi, Giuseppina; De Cola, Maria Cristina; Dell'Utri, De Cola; Melardi, Sara; Alagna, Bernardo; Bramanti, Placido; Cascio, Antonio.

In: New Microbiologica, Vol. 40, No. 2, 04.2017, p. 119-129.

Research output: Contribution to journalArticle

Barberi, G, De Cola, MC, Dell'Utri, DC, Melardi, S, Alagna, B, Bramanti, P & Cascio, A 2017, 'Antimicrobial consumption and antimicrobial resistance:a snapshot of an Italian neuromuscular rehabilitation center', New Microbiologica, vol. 40, no. 2, pp. 119-129.
Barberi, Giuseppina ; De Cola, Maria Cristina ; Dell'Utri, De Cola ; Melardi, Sara ; Alagna, Bernardo ; Bramanti, Placido ; Cascio, Antonio. / Antimicrobial consumption and antimicrobial resistance:a snapshot of an Italian neuromuscular rehabilitation center. In: New Microbiologica. 2017 ; Vol. 40, No. 2. pp. 119-129.
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