Abstract
Diet restriction, prolonging the lifespan of rodents, represents an interesting model for gerontological studies. We analyzed the activity of antioxidant enzymes, Superoxide Dismutase, Catalase and Glutathione Peroxidase in erythrocytes from young, old and old food restricted Wistar rats. Diet restriction was applied feeding the animals on every-other-day schedule starting from the age of 3.5 months. The age-dependent decrease of Catalase and Glutathione Peroxidase activities was prevented by food restriction, whereas Superoxide Dismutase activity was not influenced either by aging and dietary intervention. Present results support the hypothesis that diet restriction increases the protection of cell structure against the peroxidative damage, preserving the activity of antioxidant enzymes.
| Original language | English |
|---|---|
| Pages (from-to) | 909-914 |
| Number of pages | 6 |
| Journal | Bollettino della Societa Italiana di Biologia Sperimentale |
| Volume | 66 |
| Issue number | 10 |
| Publication status | Published - Oct 1990 |
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Antioxidant enzymes in erythrocytes from old and diet restricted old rats. / Pieri, C.; Falasca, M.; Moroni, F.; Recchioni, R.; Marcheselli, F.; Ioppolo, C.; Marmocchi, F.
In: Bollettino della Societa Italiana di Biologia Sperimentale, Vol. 66, No. 10, 10.1990, p. 909-914.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Antioxidant enzymes in erythrocytes from old and diet restricted old rats.
AU - Pieri, C.
AU - Falasca, M.
AU - Moroni, F.
AU - Recchioni, R.
AU - Marcheselli, F.
AU - Ioppolo, C.
AU - Marmocchi, F.
PY - 1990/10
Y1 - 1990/10
N2 - Diet restriction, prolonging the lifespan of rodents, represents an interesting model for gerontological studies. We analyzed the activity of antioxidant enzymes, Superoxide Dismutase, Catalase and Glutathione Peroxidase in erythrocytes from young, old and old food restricted Wistar rats. Diet restriction was applied feeding the animals on every-other-day schedule starting from the age of 3.5 months. The age-dependent decrease of Catalase and Glutathione Peroxidase activities was prevented by food restriction, whereas Superoxide Dismutase activity was not influenced either by aging and dietary intervention. Present results support the hypothesis that diet restriction increases the protection of cell structure against the peroxidative damage, preserving the activity of antioxidant enzymes.
AB - Diet restriction, prolonging the lifespan of rodents, represents an interesting model for gerontological studies. We analyzed the activity of antioxidant enzymes, Superoxide Dismutase, Catalase and Glutathione Peroxidase in erythrocytes from young, old and old food restricted Wistar rats. Diet restriction was applied feeding the animals on every-other-day schedule starting from the age of 3.5 months. The age-dependent decrease of Catalase and Glutathione Peroxidase activities was prevented by food restriction, whereas Superoxide Dismutase activity was not influenced either by aging and dietary intervention. Present results support the hypothesis that diet restriction increases the protection of cell structure against the peroxidative damage, preserving the activity of antioxidant enzymes.
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M3 - Article
C2 - 2096875
AN - SCOPUS:0025504237
VL - 66
SP - 909
EP - 914
JO - Bollettino della Societa Italiana di Biologia Sperimentale
JF - Bollettino della Societa Italiana di Biologia Sperimentale
SN - 0037-8771
IS - 10
ER -