Abstract
Background and Purpose - Experimental studies provide evidence of an association between ischemic stroke and increased oxidative stress, but data in humans are still limited and controversial. The purpose of this study was to investigate the time course of plasma antioxidant changes in ischemic stroke patients. Methods - Plasma antioxidants, including water-soluble (vitamin C and uric acid) and lipid-soluble (vitamins A and E) compounds as well as antioxidant enzyme activities in plasma (superoxide dismutase [SOD] and glutathione peroxidase) and erythrocytes (SOD), were measured by high-performance liquid chromatography (antioxidant vitamins) and by spectrophotometry (antioxidant enzymes) in 38 subjects (25 men and 13 women aged 77.2±7.9 years) with acute ischemic stroke of recent onset (
| Original language | English |
|---|---|
| Pages (from-to) | 2295-2300 |
| Number of pages | 6 |
| Journal | Stroke |
| Volume | 31 |
| Issue number | 10 |
| Publication status | Published - 2000 |
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Keywords
- Antioxidants
- Outcome
- Oxidative stress
- Stroke
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
- Neuroscience(all)
Cite this
Antioxidant profile and early outcome in stroke patients. / Cherubini, Antonio; Polidori, Maria Cristina; Bregnocchi, Mario; Pezzuto, Salvatore; Cecchetti, Roberta; Ingegni, Tiziana; Di Iorio, Angelo; Senin, Umberto; Mecocci, Patrizia.
In: Stroke, Vol. 31, No. 10, 2000, p. 2295-2300.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Antioxidant profile and early outcome in stroke patients
AU - Cherubini, Antonio
AU - Polidori, Maria Cristina
AU - Bregnocchi, Mario
AU - Pezzuto, Salvatore
AU - Cecchetti, Roberta
AU - Ingegni, Tiziana
AU - Di Iorio, Angelo
AU - Senin, Umberto
AU - Mecocci, Patrizia
PY - 2000
Y1 - 2000
N2 - Background and Purpose - Experimental studies provide evidence of an association between ischemic stroke and increased oxidative stress, but data in humans are still limited and controversial. The purpose of this study was to investigate the time course of plasma antioxidant changes in ischemic stroke patients. Methods - Plasma antioxidants, including water-soluble (vitamin C and uric acid) and lipid-soluble (vitamins A and E) compounds as well as antioxidant enzyme activities in plasma (superoxide dismutase [SOD] and glutathione peroxidase) and erythrocytes (SOD), were measured by high-performance liquid chromatography (antioxidant vitamins) and by spectrophotometry (antioxidant enzymes) in 38 subjects (25 men and 13 women aged 77.2±7.9 years) with acute ischemic stroke of recent onset (
AB - Background and Purpose - Experimental studies provide evidence of an association between ischemic stroke and increased oxidative stress, but data in humans are still limited and controversial. The purpose of this study was to investigate the time course of plasma antioxidant changes in ischemic stroke patients. Methods - Plasma antioxidants, including water-soluble (vitamin C and uric acid) and lipid-soluble (vitamins A and E) compounds as well as antioxidant enzyme activities in plasma (superoxide dismutase [SOD] and glutathione peroxidase) and erythrocytes (SOD), were measured by high-performance liquid chromatography (antioxidant vitamins) and by spectrophotometry (antioxidant enzymes) in 38 subjects (25 men and 13 women aged 77.2±7.9 years) with acute ischemic stroke of recent onset (
KW - Antioxidants
KW - Outcome
KW - Oxidative stress
KW - Stroke
UR - http://www.scopus.com/inward/record.url?scp=0033800597&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0033800597&partnerID=8YFLogxK
M3 - Article
C2 - 11022053
AN - SCOPUS:0033800597
VL - 31
SP - 2295
EP - 2300
JO - Stroke
JF - Stroke
SN - 0039-2499
IS - 10
ER -