Abstract
Background and Purpose - Experimental studies provide evidence of an association between ischemic stroke and increased oxidative stress, but data in humans are still limited and controversial. The purpose of this study was to investigate the time course of plasma antioxidant changes in ischemic stroke patients. Methods - Plasma antioxidants, including water-soluble (vitamin C and uric acid) and lipid-soluble (vitamins A and E) compounds as well as antioxidant enzyme activities in plasma (superoxide dismutase [SOD] and glutathione peroxidase) and erythrocytes (SOD), were measured by high-performance liquid chromatography (antioxidant vitamins) and by spectrophotometry (antioxidant enzymes) in 38 subjects (25 men and 13 women aged 77.2±7.9 years) with acute ischemic stroke of recent onset (
Original language | English |
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Pages (from-to) | 2295-2300 |
Number of pages | 6 |
Journal | Stroke |
Volume | 31 |
Issue number | 10 |
Publication status | Published - 2000 |
Keywords
- Antioxidants
- Outcome
- Oxidative stress
- Stroke
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
- Neuroscience(all)