Abstract
Data on the protective role of antioxidants in models of atherosclerosis are only partially confirmed in man. Observational and epidemiological data, as well as randomized trials, provide no clear cut indications, because of positive and disappointing results on the use of antioxidants in cardiovascular protection. Despite the lack of a general consensus, recent data reinforce the concept that the regular intake of antioxidants present in food limits the progression of atherosclerosis. When it is possible to monitor the efficacy of any antioxidant therapy with validated markers of oxidation, the potential influence of vitamins and antioxidants on coronary artery disease may eventually be resolved.
| Original language | English |
|---|---|
| Pages (from-to) | 541-549 |
| Number of pages | 9 |
| Journal | Current Opinion in Lipidology |
| Volume | 9 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 1998 |
Fingerprint
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
Cite this
Antioxidants and coronary artery disease. / Faggiotto, Agostino L.; Poli, Andrea; Catapano, Alberico Luigi.
In: Current Opinion in Lipidology, Vol. 9, No. 6, 1998, p. 541-549.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Antioxidants and coronary artery disease
AU - Faggiotto, Agostino L.
AU - Poli, Andrea
AU - Catapano, Alberico Luigi
PY - 1998
Y1 - 1998
N2 - Data on the protective role of antioxidants in models of atherosclerosis are only partially confirmed in man. Observational and epidemiological data, as well as randomized trials, provide no clear cut indications, because of positive and disappointing results on the use of antioxidants in cardiovascular protection. Despite the lack of a general consensus, recent data reinforce the concept that the regular intake of antioxidants present in food limits the progression of atherosclerosis. When it is possible to monitor the efficacy of any antioxidant therapy with validated markers of oxidation, the potential influence of vitamins and antioxidants on coronary artery disease may eventually be resolved.
AB - Data on the protective role of antioxidants in models of atherosclerosis are only partially confirmed in man. Observational and epidemiological data, as well as randomized trials, provide no clear cut indications, because of positive and disappointing results on the use of antioxidants in cardiovascular protection. Despite the lack of a general consensus, recent data reinforce the concept that the regular intake of antioxidants present in food limits the progression of atherosclerosis. When it is possible to monitor the efficacy of any antioxidant therapy with validated markers of oxidation, the potential influence of vitamins and antioxidants on coronary artery disease may eventually be resolved.
UR - http://www.scopus.com/inward/record.url?scp=0032435182&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032435182&partnerID=8YFLogxK
U2 - 10.1097/00041433-199812000-00005
DO - 10.1097/00041433-199812000-00005
M3 - Article
VL - 9
SP - 541
EP - 549
JO - Current Opinion in Lipidology
JF - Current Opinion in Lipidology
SN - 0957-9672
IS - 6
ER -