Antioxidants, oxidative stress, and pulmonary function in individuals diagnosed with asthma or COPD

H. M. Ochs-Balcom, B. J B Grant, P. Muti, C. T. Sempos, J. L. Freudenheim, R. W. Browne, S. E. McCann, M. Trevisan, P. A. Cassano, L. Iacoviello, H. J. Schünemann

Research output: Contribution to journalArticle

88 Citations (Scopus)

Abstract

Objective: The objective of this study was to investigate the association between antioxidant nutrients and markers of oxidative stress with pulmonary function in persons with chronic airflow limitation. Design: Cross-sectional study exploring the association of antioxidant nutrients and markers of oxidative stress with forced expiratory volume in the first second (FEV1%) and forced vital capacity (FVC%). Setting/Subjects: The study data included 218 persons with chronic airf low limitation recruited randomly from the general population of Erie and Niagara counties, New York State, USA. Results: After adjustment for covariates, multiple linear regression analysis showed that serum β-cryptoxanthin, lutein/zeaxanthin, and retinol, and dietary β-carotene, β-cryptoxanthin, lutein/ zeaxanthin, vitamin C, and lycopene were positively associated with FEV1% (P1 %, while plasma thiobarbituric acid-reactive substances (TBARS) were negatively associated with FVC% (P

Original languageEnglish
Pages (from-to)991-999
Number of pages9
JournalEuropean Journal of Clinical Nutrition
Volume60
Issue number8
DOIs
Publication statusPublished - Aug 2006

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Lutein
lung function
zeaxanthin
asthma
lutein
Chronic Obstructive Pulmonary Disease
Oxidative Stress
oxidative stress
Asthma
Antioxidants
antioxidants
Food
Lung
Thiobarbituric Acid Reactive Substances
Vital Capacity
Forced Expiratory Volume
nutrients
Carotenoids
carotenes
lycopene

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Food Science

Cite this

Ochs-Balcom, H. M., Grant, B. J. B., Muti, P., Sempos, C. T., Freudenheim, J. L., Browne, R. W., ... Schünemann, H. J. (2006). Antioxidants, oxidative stress, and pulmonary function in individuals diagnosed with asthma or COPD. European Journal of Clinical Nutrition, 60(8), 991-999. https://doi.org/10.1038/sj.ejcn.1602410

Antioxidants, oxidative stress, and pulmonary function in individuals diagnosed with asthma or COPD. / Ochs-Balcom, H. M.; Grant, B. J B; Muti, P.; Sempos, C. T.; Freudenheim, J. L.; Browne, R. W.; McCann, S. E.; Trevisan, M.; Cassano, P. A.; Iacoviello, L.; Schünemann, H. J.

In: European Journal of Clinical Nutrition, Vol. 60, No. 8, 08.2006, p. 991-999.

Research output: Contribution to journalArticle

Ochs-Balcom, HM, Grant, BJB, Muti, P, Sempos, CT, Freudenheim, JL, Browne, RW, McCann, SE, Trevisan, M, Cassano, PA, Iacoviello, L & Schünemann, HJ 2006, 'Antioxidants, oxidative stress, and pulmonary function in individuals diagnosed with asthma or COPD', European Journal of Clinical Nutrition, vol. 60, no. 8, pp. 991-999. https://doi.org/10.1038/sj.ejcn.1602410
Ochs-Balcom, H. M. ; Grant, B. J B ; Muti, P. ; Sempos, C. T. ; Freudenheim, J. L. ; Browne, R. W. ; McCann, S. E. ; Trevisan, M. ; Cassano, P. A. ; Iacoviello, L. ; Schünemann, H. J. / Antioxidants, oxidative stress, and pulmonary function in individuals diagnosed with asthma or COPD. In: European Journal of Clinical Nutrition. 2006 ; Vol. 60, No. 8. pp. 991-999.
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