Antioxidants, oxidative stress, and pulmonary function in individuals diagnosed with asthma or COPD

H. M. Ochs-Balcom, B. J B Grant, P. Muti, C. T. Sempos, J. L. Freudenheim, R. W. Browne, S. E. McCann, M. Trevisan, P. A. Cassano, L. Iacoviello, H. J. Schünemann

Research output: Contribution to journalArticle

Abstract

Objective: The objective of this study was to investigate the association between antioxidant nutrients and markers of oxidative stress with pulmonary function in persons with chronic airflow limitation. Design: Cross-sectional study exploring the association of antioxidant nutrients and markers of oxidative stress with forced expiratory volume in the first second (FEV1%) and forced vital capacity (FVC%). Setting/Subjects: The study data included 218 persons with chronic airf low limitation recruited randomly from the general population of Erie and Niagara counties, New York State, USA. Results: After adjustment for covariates, multiple linear regression analysis showed that serum β-cryptoxanthin, lutein/zeaxanthin, and retinol, and dietary β-carotene, β-cryptoxanthin, lutein/ zeaxanthin, vitamin C, and lycopene were positively associated with FEV1% (P1 %, while plasma thiobarbituric acid-reactive substances (TBARS) were negatively associated with FVC% (P

Original languageEnglish
Pages (from-to)991-999
Number of pages9
JournalEuropean Journal of Clinical Nutrition
Volume60
Issue number8
DOIs
Publication statusPublished - Aug 2006

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ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Food Science

Cite this

Ochs-Balcom, H. M., Grant, B. J. B., Muti, P., Sempos, C. T., Freudenheim, J. L., Browne, R. W., McCann, S. E., Trevisan, M., Cassano, P. A., Iacoviello, L., & Schünemann, H. J. (2006). Antioxidants, oxidative stress, and pulmonary function in individuals diagnosed with asthma or COPD. European Journal of Clinical Nutrition, 60(8), 991-999. https://doi.org/10.1038/sj.ejcn.1602410