Anton’s Syndrome associated with autotopagnosia

Viviana Lo Buono, Simona De Salvo, Giuseppe Paladina, Francesco Corallo, Rosanna Palmeri, Rosa Morabito, Alessia Bramanti, Silvia Marino, Edoardo Sessa

Research output: Contribution to journalArticlepeer-review


We describe an unusual case of a 68-year-old male affected by cerebral amyloid angiopathy and cortical blindness associated with Anton’s syndrome. In addition, our patient presented with autotopagnosia, a form of agnosia characterized by loss of body spatial representation. Neuropsychological assessment evidenced cognitive impairment. Magnetic Resonance Imaging showed hemorrhagic foci in the left occipital and right occipito-parietal lobe, paratrigonal white matter, and post-ischemic parenchymal gliosis. The pattern-reversal of visual evoked potentials were indicative bilateral visual pathway of integrity of the. After a neurological damage, patients could show a denial of their own deficit; however, the association between anosognosia and autotopagnosia represents a rare neurological condition. The simultaneous onset of unusual neuropsychological syndromes could be related to involvement of a complex brain network.

Original languageEnglish
JournalApplied Neuropsychology:Adult
Publication statusAccepted/In press - Jan 1 2018


  • Anosognosia
  • anton’s syndrome
  • autotopagnosia
  • cerebral amyloid angiopathy

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Developmental and Educational Psychology


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