Anton's Syndrome associated with autotopagnosia

Viviana Lo Buono, Simona De Salvo, Giuseppe Paladina, Francesco Corallo, Rosanna Palmeri, Rosa Morabito, Alessia Bramanti, Silvia Marino, Edoardo Sessa

Research output: Contribution to journalArticle


We describe an unusual case of a 68-year-old male affected by cerebral amyloid angiopathy and cortical blindness associated with Anton's syndrome. In addition, our patient presented with autotopagnosia, a form of agnosia characterized by loss of body spatial representation. Neuropsychological assessment evidenced cognitive impairment. Magnetic Resonance Imaging showed hemorrhagic foci in the left occipital and right occipito-parietal lobe, paratrigonal white matter, and post-ischemic parenchymal gliosis. The pattern-reversal of visual evoked potentials were indicative bilateral visual pathway of integrity of the. After a neurological damage, patients could show a denial of their own deficit; however, the association between anosognosia and autotopagnosia represents a rare neurological condition. The simultaneous onset of unusual neuropsychological syndromes could be related to involvement of a complex brain network.

Original languageEnglish
Pages (from-to)294-298
Number of pages5
JournalApplied neuropsychology. Adult
Issue number3
Publication statusPublished - Jan 22 2019


  • Aged
  • Agnosia/diagnosis
  • Blindness, Cortical/diagnosis
  • Cerebral Amyloid Angiopathy/complications
  • Cognitive Dysfunction/diagnosis
  • Electroencephalography
  • Evoked Potentials, Visual/physiology
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Perceptual Disorders/diagnosis


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