Aortic complications after bicuspid aortic valve replacement: Long-term results

Claudio F. Russo, Simone Mazzetti, Andrea Garatti, Elena Ribera, Angela Milazzo, Giuseppe Bruschi, Marco Lanfranconi, Tiziano Colombo, Ettore Vitali

Research output: Contribution to journalArticlepeer-review


Background. Bicuspid aortic valve (BAV) is a risk factor for aortic dissection and aneurysm. We studied patients with BAV and tricuspid aortic valve (TAV) to evaluate long-term changes in the ascending aorta after aortic valve replacement (AVR). Patients and Methods. One hundred consecutive patients were allocated into two groups according to the presence of BAV (group A, 50 patients) or TAV (group B, 50 patients). Mean age was 51 ± 12 years in group A, and 50 ± years 12 in group B. No patients had hypertension or Marfan's syndrome. Until July 2001, mean follow-up was 234 ± 47 months in group A and 241 ± 43 months in group B. Results. Five patients (10%, CL 5.7 to 13.9) in group A suffered late acute aortic dissection. Acute aortic dissection (5 vs 0, p = 0.0001) and sudden death (7 vs 0, p = 0.0001) occurred more frequently in patients with BAV. All survivors were assessed by echocardiogram. The mean diameter of the ascending aorta was 48.4 mm in group A and 36.8 mm in group B. Three patients in group A were operated on because of ascending aorta aneurysm more than 6 cm in diameter. Conclusions. As a result of our experience, we recommend a policy of prophylactic replacement of even a seemingly normal and definitely a mildly enlarged ascending aorta in cases of BAV at the moment of AVR, and consideration of a similar approach for any other cardiac surgical procedure in patients with BAV.

Original languageEnglish
JournalAnnals of Thoracic Surgery
Issue number5
Publication statusPublished - Nov 1 2002

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery


Dive into the research topics of 'Aortic complications after bicuspid aortic valve replacement: Long-term results'. Together they form a unique fingerprint.

Cite this