Aortic root replacement with the Carboseal composite valve graft: Analysis of risk factors

Fabrizio Settepani, Alessandro Eusebio, Diego Ornaghi, Alessandro Barbone, Enrico Citterio, Eric Manasse, Giuseppe Silvaggio, Roberto Gallotti

Research output: Contribution to journalArticlepeer-review


This retrospective analysis of a selected series of Bentall-De Bono procedures was carried out in order to evaluate the performance of the Carboseal composite valve graft (Sulzer Carbomedics Inc, Austin, TX, USA). Between October 1997 and April 2004, 120 patients underwent aortic root replacement with the Carboseal Composite Valve Graft. The mean age of patients was 59.7±13.4 years (range, 21-83 years); 96 patients (80%) were male. Eighty-nine patients (74.2%) had annulaortic ectasia, 10 patients (8.3%) post-stenotic dilatation, 3 (2.5%) post dissection aneurysm, 2 (1.7%) acute type A dissection and 1 (0.8%) endocarditis. The average follow-up duration was 29.2 months (range 2-82 months). Hospital mortality was 1.7% (2 of 120 patients). The actuarial survival rate (including hospital mortality) was 97.2±1.5% at 1 year, 91.6±3.5% at 3 years and 84.0±8.0% at 5 years. Chronic renal failure was an independent risk factor for late mortality (P=0.02). The actuarial freedom from pseudoaneurysms at 3 years was higher among patients without Marfan syndrome (94.7±3.2% vs. 75.0±21.6% at 3 years, P

Original languageEnglish
Pages (from-to)360-364
Number of pages5
JournalInteractive Cardiovascular and Thoracic Surgery
Issue number4
Publication statusPublished - Aug 1 2005


  • Aneurysm
  • Aortic root
  • Composite graft

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Pulmonary and Respiratory Medicine
  • Surgery


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