Aortic surgery in Marfan patients with severe pectus excavatum

Giuseppe Maria Raffa, Mariusz Kowalewski, Pietro Giorgio Malvindi, Alessandro Bertani, Giuseppe Romano, Sergio Sciacca, Marco Turrisi, Alessandro Armaro, Vincenzo Stringi, Giuseppe Montalbano, Gabriella Mattiucci, Fabrizio Follis, Michele Pilato

Research output: Contribution to journalReview article

Abstract

AIMS: The optimal surgical management of the aortic root phenotype Marfan patients with severe pectus excavatum is a subject of debate. All the available literature were reviewed according to preferred reporting items for systematic reviews and meta-analyses (PRISMA) principles in order to assess the early outcomes of both pectus excavatum and aortic repair techniques.

METHODS: Searches were done in PubMed and MEDLINE electronic databases dating from July 1953 to December 2015.

RESULTS: A total of 97 peer-reviewed publications were retrieved, and 27 relevant publications were identified with a total of 39 Marfan patients with pectus excavatum who underwent ascending aorta and aortic root surgery. Emergency acute Type-A aortic dissection repair was reported in five cases. Concomitant pectus excavatum and aortic root repair and composite graft implantation were the most commonly performed procedures. Complications after a staged or a combined approach were uncommon and no deaths occurred.

CONCLUSION: Aortic surgery in Marfan patients with pectus excavatum was carried out according to a variety of strategies, surgical techniques and accesses with low complications rate and no mortality. Many of these were well tolerated with minimal complications and no mortality.

Original languageEnglish
Pages (from-to)305-310
Number of pages6
JournalJournal of Cardiovascular Medicine
Volume18
Issue number5
DOIs
Publication statusPublished - May 2017

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Keywords

  • Adolescent
  • Adult
  • Aortic Aneurysm
  • Blood Vessel Prosthesis Implantation
  • Female
  • Funnel Chest
  • Humans
  • Male
  • Marfan Syndrome
  • Middle Aged
  • Orthopedic Procedures
  • Risk Assessment
  • Risk Factors
  • Severity of Illness Index
  • Sternum
  • Treatment Outcome
  • Young Adult
  • Journal Article
  • Meta-Analysis
  • Review

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