TY - JOUR
T1 - Aphasic and visual aura with increased vasogenic leakage
T2 - An atypical migrainosus status
AU - Lanfranconi, Silvia
AU - Corti, Stefania
AU - Bersano, Anna
AU - Costa, Antonella
AU - Prelle, Alessandro
AU - Sciacco, Monica
AU - Bresolin, Nereo
AU - Ghione, Isabella
PY - 2009/10/15
Y1 - 2009/10/15
N2 - The pathogenesis of migraine with aura has not been fully established yet. The release of vasoactive substances and intracranial extracerebral blood vessel vasodilatation are probably related to stimulation of meningeal blood vessels through trigeminal afferents. Here, we report a 67 year old woman developing migraine with aphasia and right hemianopsia, lasting 4 days in duration. After spontaneous recovery, she experienced the same symptoms without migraine lasting for 15 h. MRI, performed during this last episode, revealed increased perfusion and leakage of contrast into subarachnoid space. In migraine with prolonged aura hyperperfusion with vasogenic edema might explain cortical function impairment and contribute to neurological deficits.
AB - The pathogenesis of migraine with aura has not been fully established yet. The release of vasoactive substances and intracranial extracerebral blood vessel vasodilatation are probably related to stimulation of meningeal blood vessels through trigeminal afferents. Here, we report a 67 year old woman developing migraine with aphasia and right hemianopsia, lasting 4 days in duration. After spontaneous recovery, she experienced the same symptoms without migraine lasting for 15 h. MRI, performed during this last episode, revealed increased perfusion and leakage of contrast into subarachnoid space. In migraine with prolonged aura hyperperfusion with vasogenic edema might explain cortical function impairment and contribute to neurological deficits.
KW - Aura
KW - Hyperperfusion
KW - Migraine headache
KW - Status migrainosus
KW - Vasogenic edema
UR - http://www.scopus.com/inward/record.url?scp=69749117737&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=69749117737&partnerID=8YFLogxK
U2 - 10.1016/j.jns.2009.06.009
DO - 10.1016/j.jns.2009.06.009
M3 - Article
C2 - 19573879
AN - SCOPUS:69749117737
VL - 285
SP - 227
EP - 229
JO - Journal of the Neurological Sciences
JF - Journal of the Neurological Sciences
SN - 0022-510X
IS - 1-2
ER -