Aplasia cutis congenita associata a feto gemello morto in utero

Translated title of the contribution: Aplasia cutis congenita with twin fetus dead in utero

V. Di Lernia, L. Garavelli, A. Vancini, C. Magnani

Research output: Contribution to journalArticle


A case of aplasia cutis with extensive involvement of the skin of knees in a neonate is reported. No family history of aplasia cutis was present. During pregnancy, an associated monozygotic co-twin died and was resorbed in utero. On the basis of the history, absence of familial cases and clinical features (symmetry, extension, localization) the patient was diagnosed as aplasia cutis congenita type V according to Frieden's classification (aplasia cutis congenita associated with fetus papyraceus or dead fetus). Ischemic and thrombotic events in the placenta and fetus appear to be to the basis of this subtype of aplasia cutis. The passage of thromboplastic material, through intertwin vascular shunts would be able to cause chorionic thrombosis resulting in infarcts in the placenta and fetal organs, including skin in the surviving twin. In the present case, the skin defects healed after a few months with scars. No associated anomalies and malformations were discovered.

Translated title of the contributionAplasia cutis congenita with twin fetus dead in utero
Original languageItalian
Pages (from-to)697-701
Number of pages5
JournalGiornale Italiano di Dermatologia e Venereologia
Issue number6
Publication statusPublished - 2000

ASJC Scopus subject areas

  • Dermatology

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