Aplastic anaemia in childhood. Description of two cases and review of the literature

Maria Scalzone, Paola Coccia, Palma Maurizi, Giorgio Attinà, Lucia Liotti, Maria Giuseppina Cefalo, Antonio Ruggiero, Riccardo Riccardi

Research output: Contribution to journalArticlepeer-review

Abstract

Childhood aplastic anaemia (AA) is an uncommon but potentially fatal haematological disorder. Patients with AA receive supportive care based on transfusions and timely treatment of opportunistic infections, along with specific therapies, which may be bone marrow transplantation and immunosuppressive therapy. Early diagnosis and supportive therapy are required to prevent fatal complications like overwhelming sepsis or life threatening haemorrhages. We report two cases of aplastic anaemia having a different aetiology. The diagnostic work-up and the therapeutic management for each case are described below.

Original languageEnglish
Pages (from-to)363-368
Number of pages6
JournalCentral European Journal of Medicine
Volume4
Issue number3
DOIs
Publication statusPublished - Sep 2009

Keywords

  • Aplastic anaemia
  • Bone marrow transplantation
  • Immunosuppressive therapy
  • Supportive care

ASJC Scopus subject areas

  • Medicine(all)

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