APOE and modulation of Alzheimer's and frontotemporal dementia

M. Boccardi, F. Sabattoli, C. Testa, A. Beltramello, H. Soininen, G. B. Frisoni

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

To investigate the difference in the morphologic expression of frontotemporal dementia (FTD) and Alzheimer's disease (AD) in patients carrying and not carrying the ε4 allele of APOE, MR images of 26 controls, 18 AD patients (11 carrying the ε4 allele, seven non-carriers), and eight FTD (two carriers, six non-carriers) were compared using voxel by voxel analysis. Greater atrophy was found in the disease-specific regions of the ε4 carriers vs the non-carriers at P

Original languageEnglish
Pages (from-to)167-170
Number of pages4
JournalNeuroscience Letters
Volume356
Issue number3
DOIs
Publication statusPublished - Feb 19 2004

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Frontotemporal Dementia
Alzheimer Disease
Alleles
Atrophy
Alzheimer Disease 11

Keywords

  • AD
  • APOE
  • Dementia
  • Frontotemporal dementia
  • Imaging
  • Morphology
  • MR
  • Voxel based morphometry

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

APOE and modulation of Alzheimer's and frontotemporal dementia. / Boccardi, M.; Sabattoli, F.; Testa, C.; Beltramello, A.; Soininen, H.; Frisoni, G. B.

In: Neuroscience Letters, Vol. 356, No. 3, 19.02.2004, p. 167-170.

Research output: Contribution to journalArticle

Boccardi, M. ; Sabattoli, F. ; Testa, C. ; Beltramello, A. ; Soininen, H. ; Frisoni, G. B. / APOE and modulation of Alzheimer's and frontotemporal dementia. In: Neuroscience Letters. 2004 ; Vol. 356, No. 3. pp. 167-170.
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