Abstract
Forty-one Sicilian patients (22 men and 19 women) suffering from probable Alzheimer's disease (according to NINCS-ADRDA criteria) underwent APO-E genotype examination. The mean age of onset was 69.3 (DS = 6.69), and the mean period of education was 7.41 (SD = 4.18) years. Twenty-one patients reported family history of cognitive decline. Results showed that at least l allele E4 was present in 50% of patients (14: E3/4; 6: E4/4). We did not find any correlation either with age of onset (p = 0.141) or with family history (p = 0.882). These preliminary data suggest a higher percentage of E4 allele in our group of patients compared to other authors' reports (Poinier et al., 1993; Frisoni et al., 1995).
| Original language | English |
|---|---|
| Pages (from-to) | 272 |
| Number of pages | 1 |
| Journal | Italian Journal of Neurological Sciences |
| Volume | 20 |
| Issue number | 4 |
| Publication status | Published - 1999 |
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ASJC Scopus subject areas
- Neuroscience(all)
- Clinical Neurology
Cite this
Apolipoprotein e genotype in a sample of Sicilian patients suffering from Alzheimer's disease. / Ruggieri, R. M.; Palermo, R.; Calanni, P.; Forlani, G.; Lucca, U.; Greco, E.; Piccioli, F.
In: Italian Journal of Neurological Sciences, Vol. 20, No. 4, 1999, p. 272.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Apolipoprotein e genotype in a sample of Sicilian patients suffering from Alzheimer's disease
AU - Ruggieri, R. M.
AU - Palermo, R.
AU - Calanni, P.
AU - Forlani, G.
AU - Lucca, U.
AU - Greco, E.
AU - Piccioli, F.
PY - 1999
Y1 - 1999
N2 - Forty-one Sicilian patients (22 men and 19 women) suffering from probable Alzheimer's disease (according to NINCS-ADRDA criteria) underwent APO-E genotype examination. The mean age of onset was 69.3 (DS = 6.69), and the mean period of education was 7.41 (SD = 4.18) years. Twenty-one patients reported family history of cognitive decline. Results showed that at least l allele E4 was present in 50% of patients (14: E3/4; 6: E4/4). We did not find any correlation either with age of onset (p = 0.141) or with family history (p = 0.882). These preliminary data suggest a higher percentage of E4 allele in our group of patients compared to other authors' reports (Poinier et al., 1993; Frisoni et al., 1995).
AB - Forty-one Sicilian patients (22 men and 19 women) suffering from probable Alzheimer's disease (according to NINCS-ADRDA criteria) underwent APO-E genotype examination. The mean age of onset was 69.3 (DS = 6.69), and the mean period of education was 7.41 (SD = 4.18) years. Twenty-one patients reported family history of cognitive decline. Results showed that at least l allele E4 was present in 50% of patients (14: E3/4; 6: E4/4). We did not find any correlation either with age of onset (p = 0.141) or with family history (p = 0.882). These preliminary data suggest a higher percentage of E4 allele in our group of patients compared to other authors' reports (Poinier et al., 1993; Frisoni et al., 1995).
UR - http://www.scopus.com/inward/record.url?scp=33746368065&partnerID=8YFLogxK
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M3 - Article
AN - SCOPUS:33746368065
VL - 20
SP - 272
JO - Italian Journal of Neurological Sciences
JF - Italian Journal of Neurological Sciences
SN - 0392-0461
IS - 4
ER -