Abstract
Two distinct pathways for cell death exist. Compared to necrotic death, physiological or apoptotic cell death is an active suicidal process that consists of a cascade of well-regulated synthetic events. Participation of specific genes in apoptosis, and its possible molecular regulation, are considered in order to investigate the mechanism of cell death induced by some cancer chemotherapeutic agents.
| Original language | English |
|---|---|
| Pages (from-to) | 122-127 |
| Number of pages | 6 |
| Journal | FEBS Letters |
| Volume | 307 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jul 27 1992 |
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Keywords
- Anticancer agent
- bcl-2
- Calcium
- Cell cycle phase
- p34, p53
- Programmed cell death
- Regulation
- Sulphated glycoprotein
ASJC Scopus subject areas
- Biochemistry
- Biophysics
- Molecular Biology
Cite this
Apoptosis Biochemical events and relevance to cancer chemotherapy. / Sen, Soumitra; D'Incalci, Maurizio.
In: FEBS Letters, Vol. 307, No. 1, 27.07.1992, p. 122-127.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Apoptosis Biochemical events and relevance to cancer chemotherapy
AU - Sen, Soumitra
AU - D'Incalci, Maurizio
PY - 1992/7/27
Y1 - 1992/7/27
N2 - Two distinct pathways for cell death exist. Compared to necrotic death, physiological or apoptotic cell death is an active suicidal process that consists of a cascade of well-regulated synthetic events. Participation of specific genes in apoptosis, and its possible molecular regulation, are considered in order to investigate the mechanism of cell death induced by some cancer chemotherapeutic agents.
AB - Two distinct pathways for cell death exist. Compared to necrotic death, physiological or apoptotic cell death is an active suicidal process that consists of a cascade of well-regulated synthetic events. Participation of specific genes in apoptosis, and its possible molecular regulation, are considered in order to investigate the mechanism of cell death induced by some cancer chemotherapeutic agents.
KW - Anticancer agent
KW - bcl-2
KW - Calcium
KW - Cell cycle phase
KW - p34, p53
KW - Programmed cell death
KW - Regulation
KW - Sulphated glycoprotein
UR - http://www.scopus.com/inward/record.url?scp=0026638951&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0026638951&partnerID=8YFLogxK
U2 - 10.1016/0014-5793(92)80914-3
DO - 10.1016/0014-5793(92)80914-3
M3 - Article
C2 - 1639187
AN - SCOPUS:0026638951
VL - 307
SP - 122
EP - 127
JO - FEBS Letters
JF - FEBS Letters
SN - 0014-5793
IS - 1
ER -