The apparent dissociation constants for uracil metabolites of methylxanthines have been determined by following the change of extinction coefficient of the ultraviolet spectra of compounds in different ionized states as a function of pH. The relationship between observed spectral changes and ionization state is discussed. A summary picture is reported for all caffeine metabolites.
- Apparent dissociation constant (pK)
- Caffeine Methylxanthines Uracils
- UV spectroscopy
ASJC Scopus subject areas
- Analytical Chemistry
- Biochemistry, medical
- Clinical Biochemistry