Application of a computerised method to measure static pressure volume curve in acute respiratory distress syndrome

G. Servillo, E. De Robertis, M. Coppola, F. Blasi, F. Rossano, R. Tufano

Research output: Contribution to journalArticlepeer-review


Objective: To assess the safety and the bedside feasibility of a new computerised method to record the static pressure-volume curves (Pst/V) of the respiratory system. Design: The Pst/V curves were recorded in 13 medical patients with the acute respiratory distress syndrome (ARDS). During the Pst/V curve tracing the following parameters were recorded: time required for the recording and the automatic analysis of the Pst/V curve and modifications in electrocardiograms, blood pressure, and arterial oxygen satmation (SaO2). Setting: The study was performed in the intensive care unit of the University of Naples 'Federico II'. Results: No statistically significant modifications in heart rate (HR, b min-1), blood pressure (BP, mmHg), and SaO2 were observed between conditions at baseline (HR 97.2 ± 17.7; BP 65.4 ± 9.3; SaO2 93.6 ± 2.0), during the recording (HR 99.8 ± 19.5; BP 66.2 ± 11.6; SaO2 93.7 ± 2.4), and 2 min after the procedure (HR 98.2 ± 17.8; BP 65.2 ± 11.7; SaO2 93.7 ± 1.9). The Pst/V curves were recorded in 8.38 ± 1.19 min and fully analysed in 2.69 ± 0.85 min. Mean value of static compliance was 41.1 ± 12.7 ml cmH2O-1. A lower inflection point was found in ten patients (mean value 9.2 ± 1.9 cmH2O). Conclusions: In ARDS patients, the present new computerised method gave valuable data to ordinary intensivists and was shown to be safe, easy, and fast.

Original languageEnglish
Pages (from-to)11-14
Number of pages4
JournalIntensive Care Medicine
Issue number1
Publication statusPublished - 2000


  • Acute respiratory distress syndrome
  • Static compliance
  • Static pressure volume curve

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine


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