Application of higher-order spectral analysis to local field potentials recorded in patients treated with deep brain stimulation

Sara Marceglia, Anna Maria Bianchi, Guglielmo Foffani, Alberto Priori, Sergio Cerutti

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Local field potentials (LFPs) recorded from implanted deep brain electrodes demonstrated the oscillatory nature of human basal ganglia. LFP rhythms were mainly characterized by means od power spectral analysis, thus loosing information related to rhythm phase synchronization and to event related phase modulations. Because the application of higher-order spectral analysis methodology can overcome such limitation, here we review the present applications of bispectral and cross-bispectral analysis to LFP recordings. The results obtained up to now showed that higher-order spectral analysis was able to clarify detect different rhythm synchronizations and interactions characterizing different pathologies and patient's states.

Original languageEnglish
Title of host publicationProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages5549-5552
Number of pages4
Volume2015-November
ISBN (Print)9781424492718
DOIs
Publication statusPublished - Nov 4 2015
Event37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015 - Milan, Italy
Duration: Aug 25 2015Aug 29 2015

Other

Other37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015
CountryItaly
CityMilan
Period8/25/158/29/15

Fingerprint

Deep Brain Stimulation
Basal Ganglia
Spectrum analysis
Brain
Electrodes
Pathology
Synchronization
Phase modulation

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Biomedical Engineering
  • Health Informatics

Cite this

Marceglia, S., Bianchi, A. M., Foffani, G., Priori, A., & Cerutti, S. (2015). Application of higher-order spectral analysis to local field potentials recorded in patients treated with deep brain stimulation. In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS (Vol. 2015-November, pp. 5549-5552). [7319649] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC.2015.7319649

Application of higher-order spectral analysis to local field potentials recorded in patients treated with deep brain stimulation. / Marceglia, Sara; Bianchi, Anna Maria; Foffani, Guglielmo; Priori, Alberto; Cerutti, Sergio.

Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. Vol. 2015-November Institute of Electrical and Electronics Engineers Inc., 2015. p. 5549-5552 7319649.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Marceglia, S, Bianchi, AM, Foffani, G, Priori, A & Cerutti, S 2015, Application of higher-order spectral analysis to local field potentials recorded in patients treated with deep brain stimulation. in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. vol. 2015-November, 7319649, Institute of Electrical and Electronics Engineers Inc., pp. 5549-5552, 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015, Milan, Italy, 8/25/15. https://doi.org/10.1109/EMBC.2015.7319649
Marceglia S, Bianchi AM, Foffani G, Priori A, Cerutti S. Application of higher-order spectral analysis to local field potentials recorded in patients treated with deep brain stimulation. In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. Vol. 2015-November. Institute of Electrical and Electronics Engineers Inc. 2015. p. 5549-5552. 7319649 https://doi.org/10.1109/EMBC.2015.7319649
Marceglia, Sara ; Bianchi, Anna Maria ; Foffani, Guglielmo ; Priori, Alberto ; Cerutti, Sergio. / Application of higher-order spectral analysis to local field potentials recorded in patients treated with deep brain stimulation. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. Vol. 2015-November Institute of Electrical and Electronics Engineers Inc., 2015. pp. 5549-5552
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