Application of microarray-based technology to neuroblastoma

Paola Scaruffi, Alexander Valent, Alexander Schramm, Kathy Astrahantseff, Angelika Eggert, Gian Paolo Tonini

Research output: Contribution to journalArticlepeer-review

Abstract

In the past decade, microarray technology has become a major tool for high-throughput comprehensive analysis of gene expression, genotyping and re-sequencing applications. High-throughput microarrays are used for expression profiling analyses with the aims of gene or pathway discovery, tumor subclassification or relapse risk assessment. The introduction of microarray CGH provides a powerful tool to precisely detect and quantify genomic aberrations and map these directly onto the human genome. This review summarizes the current status of the application of microarray technology to neuroblastoma research.

Original languageEnglish
Pages (from-to)13-20
Number of pages8
JournalCancer Letters
Volume228
Issue number1-2
DOIs
Publication statusPublished - Oct 18 2005

Keywords

  • Array-CGH
  • Gene expression profiling
  • Microarray
  • Neuroblastoma

ASJC Scopus subject areas

  • Cancer Research
  • Molecular Biology
  • Oncology

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