Application of ripple mapping to visualize slow conduction channels within the infarct-related left ventricular scar

Shahnaz Jamil-Copley, Pasquale Vergara, Corrado Carbucicchio, Nick Linton, Michael Koa-Wing, Vishal Luther, Darrel P. Francis, Nicholas S. Peters, David Wyn Davies, Claudio Tondo, Paolo Della Bella, Prapa Kanagaratnam

Research output: Contribution to journalArticle

Abstract

Background - Ripple mapping (RM) displays each electrogram at its 3-dimensional coordinate as a bar changing in length according to its voltage-time relationship with a fiduciary reference. We applied RM to left ventricular ischemic scar for evidence of slow-conducting channels that may act as ventricular tachycardia (VT) substrate. Methods and Results - CARTO-3(Biosense Webster Inc, Diamond Bar, CA) maps in patient undergoing VT ablation were analyzed on an offline MatLab RM system. Scar was assessed for sequential movement of ripple bars, during sinus rhythm or pacing, which were distinct from surrounding tissue and termed RM conduction channels (RMCC). Conduction velocity was measured within RMCCs and compared with the healthy myocardium (>1.5 mV). In 21 maps, 77 RMCCs were identified. Conduction velocity in RMCCs was slower when compared with normal left ventricular myocardium (median, 54 [interquartile range, 40-86] versus 150 [interquartile range, 120-160] cm/s; P

Original languageEnglish
Pages (from-to)76-86
Number of pages11
JournalCirculation: Arrhythmia and Electrophysiology
Volume8
Issue number1
DOIs
Publication statusPublished - Feb 28 2015

Keywords

  • myocardial ischemia
  • tachycardia, ventricular

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)
  • Medicine(all)

Fingerprint Dive into the research topics of 'Application of ripple mapping to visualize slow conduction channels within the infarct-related left ventricular scar'. Together they form a unique fingerprint.

  • Cite this