Appraisal of disease-specific benefits of minimally invasiveness in surgery of breast cancer liver metastases

Francesca Ratti, Matteo Serenari, Matteo Zanello, Enrico Prosperi, Federica Cipriani, Giorgio Ercolani, Elio Jovine, Matteo Cescon, Luca Aldrighetti

Research output: Contribution to journalArticlepeer-review

Abstract

Background: The primary endpoint of this study is to analyze short term benefit of laparoscopic approach (minimally invasive liver surgery [MILS]) over the open techniques in patients submitted to surgery for breast cancer liver metastases (BCLM) within a disease-specific perspective. Material and Methods: A group of 30 patients who underwent laparoscopic liver resection for BCLM constituted the Study group (MILS group) and was matched in a ratio of 1:2 with patients who underwent open surgery for BCLM (Open group, constituting the Control group). Results: MILS approach resulted in a statistically significant lower blood loss (150 vs 300 mL; P <.05). The rate of postoperative complications was similar (13.3% and 16.6% in the MILS and Open groups, respectively). MILS approach was associated with a shorter length of postoperative stay (4 ± 2 days) compared with the Open group (7 ± 3 days), allowing a faster return to adjuvant treatments. Both MILS and open groups showed adequate oncological radicality, with comparable long-term results. Conclusion: MILS approach to BCLM represents the optimal instrument to obtain an adequate disease clearance in the selected group of patients candidates to surgery: the type of procedure (minor resections for limited hepatic disease) and characteristics of patients contribute to enhance the feasibility and the benefits of the laparoscopic technique.

Original languageEnglish
Pages (from-to)1169-1176
Number of pages8
JournalJournal of Surgical Oncology
Volume120
Issue number7
DOIs
Publication statusPublished - Dec 1 2019

Keywords

  • breast cancer
  • laparoscopy
  • liver metastases
  • liver resection
  • outcome

ASJC Scopus subject areas

  • Surgery
  • Oncology

Fingerprint Dive into the research topics of 'Appraisal of disease-specific benefits of minimally invasiveness in surgery of breast cancer liver metastases'. Together they form a unique fingerprint.

Cite this