Approach to small fiber neuropathy

Giuseppe Lauria, Ingemar S J Merkies, Stephen G. Waxman, Catharina G. Faber

Research output: Chapter in Book/Report/Conference proceedingChapter


Small fiber neuropathy (SFN) is due to damage of small-caliber somatic and/or autonomic nerve fibers. It often results in neuropathic pain which may dominate the clinical picture. This chapter discusses the small nerve fibers, thermosensory and nociceptive functions, and small fiber neuropathy. It also includes a brief discussion of testing of small and autonomic fiber functions, though more detailed descriptions are highlighted in Chaps. 10, 11, and 13. Neuropathic pain is discussed in Chap. 80.

Original languageEnglish
Title of host publicationNeuromuscular Disorders in Clinical Practice
PublisherSpringer New York
Number of pages11
ISBN (Print)9781461465676, 1461465664, 9781461465669
Publication statusPublished - Nov 1 2014


  • intraepidermal nerve fiber density quantification
  • nociceptive fibers
  • painful neuropathy
  • skin biopsy
  • small fiber neuropathy

ASJC Scopus subject areas

  • Medicine(all)


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