TY - JOUR
T1 - Approaches to treatments of chronic migraine associated with medication overuse
T2 - a comparison between different intensity regimens
AU - Raggi, A.
AU - Schiavolin, S.
AU - Leonardi, M.
AU - Grazzi, L.
AU - Usai, S.
AU - Curone, M.
AU - D’Amico, D.
PY - 2015/5/30
Y1 - 2015/5/30
N2 - Treatment of chronic migraine with medication overuse requires withdrawal from acute medications. However, guidelines and clear indications for different intensity regimens, i.e., day hospital (DH) vs. inpatient treatment, are not available. Patients completed disability, quality of life (QoL) and depression questionnaires; headaches frequency and overused medications category were collected. Mann–Whitney U test and Chi square were used to assess differences between inpatients and DH patients; Bonferroni correction was applied. 194 patients aged 43.9 ± 12 (160 females) were enrolled (100 from DH, 94 inpatients). Inpatients were older, less educated and with lower employment rates. Inpatients had higher MIDAS scores (P = 0.003) and headache frequency (P = 0.002). They had lower QoL for restrictive (P = 0.002) and preventive components; no difference was found for disability, mood state and QoL emotional component. Patients treated during hospitalization had higher disease severity and lower quality of life, but similar disability and mood state than those treated in DH.
AB - Treatment of chronic migraine with medication overuse requires withdrawal from acute medications. However, guidelines and clear indications for different intensity regimens, i.e., day hospital (DH) vs. inpatient treatment, are not available. Patients completed disability, quality of life (QoL) and depression questionnaires; headaches frequency and overused medications category were collected. Mann–Whitney U test and Chi square were used to assess differences between inpatients and DH patients; Bonferroni correction was applied. 194 patients aged 43.9 ± 12 (160 females) were enrolled (100 from DH, 94 inpatients). Inpatients were older, less educated and with lower employment rates. Inpatients had higher MIDAS scores (P = 0.003) and headache frequency (P = 0.002). They had lower QoL for restrictive (P = 0.002) and preventive components; no difference was found for disability, mood state and QoL emotional component. Patients treated during hospitalization had higher disease severity and lower quality of life, but similar disability and mood state than those treated in DH.
KW - Chronic migraine
KW - Disability evaluation
KW - Health-related quality of life
KW - Medication overuse
KW - Withdrawal
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U2 - 10.1007/s10072-015-2134-0
DO - 10.1007/s10072-015-2134-0
M3 - Article
C2 - 26017502
AN - SCOPUS:84931265673
VL - 36
SP - 5
EP - 8
JO - Neurological Sciences
JF - Neurological Sciences
SN - 1590-1874
ER -