TY - JOUR
T1 - Appropriateness of surgical antimicrobial prophylaxis in the Latium Region of Italy, 2008
T2 - A multicenter study
AU - Pittalis, Silvia
AU - Ferraro, Federica
AU - Piselli, Pierluca
AU - Ruscitti, Luca Enrico
AU - Grilli, Elisabetta
AU - Lanini, Simone
AU - Ippolito, Giuseppe
AU - Puro, Vincenzo
PY - 2013/8/1
Y1 - 2013/8/1
N2 - Background: There is still wide variability in surgical antimicrobial prophylaxis (SAP) practice by different surgical teams and specialties, with potential impact on adverse events and the emergence of antibiotic resistance. Methods: We assessed SAP appropriateness in a regional prospective multicenter study on the basis of the agreement of the Surgical Care Improvement Project indicators (SCIP-Inf) with Italian guidelines (GL). Results: Prophylaxis was administered in 2,664 of 2,835 procedures (94%): In 2,346 of 2,468 (95%) as indicated and in 318 of 367 (86.6%) in which they were not indicated. The SCIP-Inf1 (timing), SCIP-Inf2 (antibiotic choice), and SCIP-Inf3 (duration) were in agreement with GL in 1,172 (50%), 1,983 (84.5%), and 1,121 (48%) of 2,346 procedures, respectively. Conclusions: These results suggest the need for implementation of an antimicrobial stewardship program in this surgical setting.
AB - Background: There is still wide variability in surgical antimicrobial prophylaxis (SAP) practice by different surgical teams and specialties, with potential impact on adverse events and the emergence of antibiotic resistance. Methods: We assessed SAP appropriateness in a regional prospective multicenter study on the basis of the agreement of the Surgical Care Improvement Project indicators (SCIP-Inf) with Italian guidelines (GL). Results: Prophylaxis was administered in 2,664 of 2,835 procedures (94%): In 2,346 of 2,468 (95%) as indicated and in 318 of 367 (86.6%) in which they were not indicated. The SCIP-Inf1 (timing), SCIP-Inf2 (antibiotic choice), and SCIP-Inf3 (duration) were in agreement with GL in 1,172 (50%), 1,983 (84.5%), and 1,121 (48%) of 2,346 procedures, respectively. Conclusions: These results suggest the need for implementation of an antimicrobial stewardship program in this surgical setting.
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U2 - 10.1089/sur.2012.189
DO - 10.1089/sur.2012.189
M3 - Article
C2 - 23848414
AN - SCOPUS:84883021896
VL - 14
SP - 381
EP - 384
JO - Surgical Infections
JF - Surgical Infections
SN - 1096-2964
IS - 4
ER -