TY - JOUR
T1 - Aquarium-borne Mycobacterium marinum skin infection. report of 15 cases and review of the literature
AU - Bonamonte, Domenico
AU - De Vito, Daniela
AU - Vestita, Michelangelo
AU - Delvecchio, Susanna
AU - Ranieri, Luigi Davide
AU - Santantonio, Marilina
AU - Angelini, Gianni
PY - 2013/7
Y1 - 2013/7
N2 - Mycobacterium marinum is a non-tuberculous photochromogenic mycobacterium, commonly responsible for fish and amphibious infections world-wide. Contagion in humans typically follows minor hand trauma from aquarium keeping and manifests as a granulomatous infection of the skin. Dissemination is rare and almost exclusive to immunosuppressed hosts. 15cases ofM. marinumfish tank related infection are hereby reported. The site of infection was the upper limbs in all cases. 3 patients presented a single papulo-verrucous lesion, while the remaining 12 showed a sporotrichoid clinical pattern. Diagnosis was reached byhistory and clinical examination and further supported by one or more of the following criteria: histology, culture, acid fast bacilli identification from histologic specimen and PCR. 2 to 3 months minocycline treatment showed efficacy in 13 individuals, another case was treated with rifampicin-isoniazid association, yet another showed spontaneous regression over a 3 month period.
AB - Mycobacterium marinum is a non-tuberculous photochromogenic mycobacterium, commonly responsible for fish and amphibious infections world-wide. Contagion in humans typically follows minor hand trauma from aquarium keeping and manifests as a granulomatous infection of the skin. Dissemination is rare and almost exclusive to immunosuppressed hosts. 15cases ofM. marinumfish tank related infection are hereby reported. The site of infection was the upper limbs in all cases. 3 patients presented a single papulo-verrucous lesion, while the remaining 12 showed a sporotrichoid clinical pattern. Diagnosis was reached byhistory and clinical examination and further supported by one or more of the following criteria: histology, culture, acid fast bacilli identification from histologic specimen and PCR. 2 to 3 months minocycline treatment showed efficacy in 13 individuals, another case was treated with rifampicin-isoniazid association, yet another showed spontaneous regression over a 3 month period.
KW - Fish tank granuloma
KW - Minocycline
KW - Mycobacteriosis
KW - Mycobacterium marinum
KW - Spontaneous regression
KW - Tuberculin skin testing
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M3 - Article
C2 - 24002023
AN - SCOPUS:84884359980
VL - 23
SP - 510
EP - 516
JO - European Journal of Dermatology
JF - European Journal of Dermatology
SN - 1167-1122
IS - 4
ER -