Abstract
The animal experiments confirm that high cholesterol levels in plasma may affect platelet aggregation, with a mechanism involving modification of platelet membrane function, inducing a hyperaggregability similar to that of platelets from human subjects with type II A hypercholesteremia. This effect may be counteracted or prevented by treatment with metformin, a drug which does not affect plasma cholesterol levels, but increases platelet membrane fluidity.
| Original language | Italian |
|---|---|
| Pages (from-to) | 213-216 |
| Number of pages | 4 |
| Journal | Giornale della Arteriosclerosi |
| Volume | 7 |
| Issue number | 1 |
| Publication status | Published - 1982 |
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ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
METABOLITE DELL'ACIDO ARACHIDONICO E LORO INTERAZIONE TRA PIASTRINE E PARETE ARTERIOSA. / Paoletti, R.; Tremoli, E.
In: Giornale della Arteriosclerosi, Vol. 7, No. 1, 1982, p. 213-216.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - METABOLITE DELL'ACIDO ARACHIDONICO E LORO INTERAZIONE TRA PIASTRINE E PARETE ARTERIOSA
AU - Paoletti, R.
AU - Tremoli, E.
PY - 1982
Y1 - 1982
N2 - The animal experiments confirm that high cholesterol levels in plasma may affect platelet aggregation, with a mechanism involving modification of platelet membrane function, inducing a hyperaggregability similar to that of platelets from human subjects with type II A hypercholesteremia. This effect may be counteracted or prevented by treatment with metformin, a drug which does not affect plasma cholesterol levels, but increases platelet membrane fluidity.
AB - The animal experiments confirm that high cholesterol levels in plasma may affect platelet aggregation, with a mechanism involving modification of platelet membrane function, inducing a hyperaggregability similar to that of platelets from human subjects with type II A hypercholesteremia. This effect may be counteracted or prevented by treatment with metformin, a drug which does not affect plasma cholesterol levels, but increases platelet membrane fluidity.
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UR - http://www.scopus.com/inward/citedby.url?scp=0020321763&partnerID=8YFLogxK
M3 - Articolo
AN - SCOPUS:0020321763
VL - 7
SP - 213
EP - 216
JO - Giornale della Arteriosclerosi
JF - Giornale della Arteriosclerosi
SN - 0017-0224
IS - 1
ER -