METABOLITE DELL'ACIDO ARACHIDONICO E LORO INTERAZIONE TRA PIASTRINE E PARETE ARTERIOSA

Translated title of the contribution: Arachidonic acid metabolites in the interaction between platelets and arterial walls

R. Paoletti, E. Tremoli

Research output: Contribution to journalArticle

Abstract

The animal experiments confirm that high cholesterol levels in plasma may affect platelet aggregation, with a mechanism involving modification of platelet membrane function, inducing a hyperaggregability similar to that of platelets from human subjects with type II A hypercholesteremia. This effect may be counteracted or prevented by treatment with metformin, a drug which does not affect plasma cholesterol levels, but increases platelet membrane fluidity.

Original languageItalian
Pages (from-to)213-216
Number of pages4
JournalGiornale della Arteriosclerosi
Volume7
Issue number1
Publication statusPublished - 1982

Fingerprint

Arachidonic Acid
Blood Platelets
Hypercholesterolemia
Membrane Fluidity
Metformin
Platelet Aggregation
Cholesterol
Membranes
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

METABOLITE DELL'ACIDO ARACHIDONICO E LORO INTERAZIONE TRA PIASTRINE E PARETE ARTERIOSA. / Paoletti, R.; Tremoli, E.

In: Giornale della Arteriosclerosi, Vol. 7, No. 1, 1982, p. 213-216.

Research output: Contribution to journalArticle

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