METABOLITE DELL'ACIDO ARACHIDONICO E LORO INTERAZIONE TRA PIASTRINE E PARETE ARTERIOSA

Translated title of the contribution: Arachidonic acid metabolites in the interaction between platelets and arterial walls

R. Paoletti, E. Tremoli

Research output: Contribution to journalArticlepeer-review

Abstract

The animal experiments confirm that high cholesterol levels in plasma may affect platelet aggregation, with a mechanism involving modification of platelet membrane function, inducing a hyperaggregability similar to that of platelets from human subjects with type II A hypercholesteremia. This effect may be counteracted or prevented by treatment with metformin, a drug which does not affect plasma cholesterol levels, but increases platelet membrane fluidity.

Translated title of the contributionArachidonic acid metabolites in the interaction between platelets and arterial walls
Original languageItalian
Pages (from-to)213-216
Number of pages4
JournalGiornale della Arteriosclerosi
Volume7
Issue number1
Publication statusPublished - 1982

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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