Abstract
The animal experiments confirm that high cholesterol levels in plasma may affect platelet aggregation, with a mechanism involving modification of platelet membrane function, inducing a hyperaggregability similar to that of platelets from human subjects with type II A hypercholesteremia. This effect may be counteracted or prevented by treatment with metformin, a drug which does not affect plasma cholesterol levels, but increases platelet membrane fluidity.
| Translated title of the contribution | Arachidonic acid metabolites in the interaction between platelets and arterial walls |
|---|---|
| Original language | Italian |
| Pages (from-to) | 213-216 |
| Number of pages | 4 |
| Journal | Giornale della Arteriosclerosi |
| Volume | 7 |
| Issue number | 1 |
| Publication status | Published - 1982 |
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine