Are model-based clustering and neural clustering consistent? A case study from bioinformatics

Davide Bacciu; Elia Biganzoli; Paulo J G Lisboa; Antonina Starita

doi:10.1007/978-3-540-85565-1-23

Are model-based clustering and neural clustering consistent? A case study from bioinformatics

Davide Bacciu, Elia Biganzoli, Paulo J G Lisboa, Antonina Starita

Fondazione IRCCS Istituto Nazionale dei Tumori

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

A novel neural network clustering algorithm, CoRe, is benchmarked against previously published results on a breast cancer data set and applying the method of Partition Around Medoids (PAM). The data serve to compare the samples partitions obtained with the neural network, PAM and model-based algorithms, namely Gaussian Mixture Model (GMM), Variational Bayesian Gaussian Mixture (VBG) and Variational Bayesian Mixtures with Splitting (VBS). It is found that CoRe, on the one hand, agrees with the previously published partitions; on the other hand, it supports the existence of a supplementary cluster that we hypothesize to be an additional tumor subgroup with respect to those previously identified by PAM.

Original language	English
Title of host publication	Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Pages	181-188
Number of pages	8
Volume	5178 LNAI
Edition	PART 2
DOIs	https://doi.org/10.1007/978-3-540-85565-1-23
Publication status	Published - 2008
Event	12th International Conference on Knowledge-Based Intelligent Information and Engineering Systems, KES 2008 - Zagreb, Croatia Duration: Sep 3 2008 → Sep 5 2008

Publication series

Name	Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Number	PART 2
Volume	5178 LNAI
ISSN (Print)	03029743
ISSN (Electronic)	16113349

Other

Other	12th International Conference on Knowledge-Based Intelligent Information and Engineering Systems, KES 2008
Country	Croatia
City	Zagreb
Period	9/3/08 → 9/5/08

ASJC Scopus subject areas

Computer Science(all)
Theoretical Computer Science

Access to Document

10.1007/978-3-540-85565-1-23

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Cite this

Bacciu, D., Biganzoli, E., Lisboa, P. J. G., & Starita, A. (2008). Are model-based clustering and neural clustering consistent? A case study from bioinformatics. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) (PART 2 ed., Vol. 5178 LNAI, pp. 181-188). (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 5178 LNAI, No. PART 2). https://doi.org/10.1007/978-3-540-85565-1-23

Are model-based clustering and neural clustering consistent? A case study from bioinformatics. / Bacciu, Davide; Biganzoli, Elia; Lisboa, Paulo J G; Starita, Antonina.

Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). Vol. 5178 LNAI PART 2. ed. 2008. p. 181-188 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 5178 LNAI, No. PART 2).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Bacciu, D, Biganzoli, E, Lisboa, PJG & Starita, A 2008, Are model-based clustering and neural clustering consistent? A case study from bioinformatics. in Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). PART 2 edn, vol. 5178 LNAI, Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), no. PART 2, vol. 5178 LNAI, pp. 181-188, 12th International Conference on Knowledge-Based Intelligent Information and Engineering Systems, KES 2008, Zagreb, Croatia, 9/3/08. https://doi.org/10.1007/978-3-540-85565-1-23

Bacciu D, Biganzoli E, Lisboa PJG, Starita A. Are model-based clustering and neural clustering consistent? A case study from bioinformatics. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). PART 2 ed. Vol. 5178 LNAI. 2008. p. 181-188. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); PART 2). https://doi.org/10.1007/978-3-540-85565-1-23

Bacciu, Davide ; Biganzoli, Elia ; Lisboa, Paulo J G ; Starita, Antonina. / Are model-based clustering and neural clustering consistent? A case study from bioinformatics. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). Vol. 5178 LNAI PART 2. ed. 2008. pp. 181-188 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); PART 2).

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