TY - GEN
T1 - Are model-based clustering and neural clustering consistent? A case study from bioinformatics
AU - Bacciu, Davide
AU - Biganzoli, Elia
AU - Lisboa, Paulo J G
AU - Starita, Antonina
PY - 2008
Y1 - 2008
N2 - A novel neural network clustering algorithm, CoRe, is benchmarked against previously published results on a breast cancer data set and applying the method of Partition Around Medoids (PAM). The data serve to compare the samples partitions obtained with the neural network, PAM and model-based algorithms, namely Gaussian Mixture Model (GMM), Variational Bayesian Gaussian Mixture (VBG) and Variational Bayesian Mixtures with Splitting (VBS). It is found that CoRe, on the one hand, agrees with the previously published partitions; on the other hand, it supports the existence of a supplementary cluster that we hypothesize to be an additional tumor subgroup with respect to those previously identified by PAM.
AB - A novel neural network clustering algorithm, CoRe, is benchmarked against previously published results on a breast cancer data set and applying the method of Partition Around Medoids (PAM). The data serve to compare the samples partitions obtained with the neural network, PAM and model-based algorithms, namely Gaussian Mixture Model (GMM), Variational Bayesian Gaussian Mixture (VBG) and Variational Bayesian Mixtures with Splitting (VBS). It is found that CoRe, on the one hand, agrees with the previously published partitions; on the other hand, it supports the existence of a supplementary cluster that we hypothesize to be an additional tumor subgroup with respect to those previously identified by PAM.
UR - http://www.scopus.com/inward/record.url?scp=57749206160&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=57749206160&partnerID=8YFLogxK
U2 - 10.1007/978-3-540-85565-1-23
DO - 10.1007/978-3-540-85565-1-23
M3 - Conference contribution
AN - SCOPUS:57749206160
SN - 3540855645
SN - 9783540855644
VL - 5178 LNAI
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 181
EP - 188
BT - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
T2 - 12th International Conference on Knowledge-Based Intelligent Information and Engineering Systems, KES 2008
Y2 - 3 September 2008 through 5 September 2008
ER -