Abstract
An x-ray diffractometric technique was used to study the crystalline composition of gallstones removed during surgery from 106 patients. Monohydrate cholesterol was found in the stones of 70 (66%) patients, either alone (33%) or in association with calcium salts (33%). The anhydrous form of cholesterol was found in the stones of 28 (26%) patients, either alone (10%) or in association with calcium salts (16%). These salts (vaterite, aragonite, and calcite) were found in 50% of cases in varying amounts (from 12% to 15% of the stone weight). Eight stones contained no cholesterol: 4 showed an amorphous pattern and 4 were composed of calcium carbonate salts. In 7 of 8 patients with bile duct stones concomitant with gallbladder stones, results of the diffractograms of the stones from the two different sites were comparable, even in 4 cases in which the stones were macroscopically different. Neither the macroscopic appearance nor the chemical structure of the stones appeared to be influenced by the patient's sex.
| Original language | English |
|---|---|
| Pages (from-to) | 1169-1175 |
| Number of pages | 7 |
| Journal | Current Therapeutic Research |
| Volume | 55 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - 1994 |
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Are morphology and composition of gallstones related? An x-ray diffraction study. / Bassi, N.; Del Favero, G.; Meggiato, T.; Scalon, P.; Ghiro, S.; Molin, M.; Pilotto, A.; Vigneri, S.; Savarino, V.; Mela, G. S.; Di Mario, F.
In: Current Therapeutic Research, Vol. 55, No. 10, 1994, p. 1169-1175.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Are morphology and composition of gallstones related? An x-ray diffraction study
AU - Bassi, N.
AU - Del Favero, G.
AU - Meggiato, T.
AU - Scalon, P.
AU - Ghiro, S.
AU - Molin, M.
AU - Pilotto, A.
AU - Vigneri, S.
AU - Savarino, V.
AU - Mela, G. S.
AU - Di Mario, F.
PY - 1994
Y1 - 1994
N2 - An x-ray diffractometric technique was used to study the crystalline composition of gallstones removed during surgery from 106 patients. Monohydrate cholesterol was found in the stones of 70 (66%) patients, either alone (33%) or in association with calcium salts (33%). The anhydrous form of cholesterol was found in the stones of 28 (26%) patients, either alone (10%) or in association with calcium salts (16%). These salts (vaterite, aragonite, and calcite) were found in 50% of cases in varying amounts (from 12% to 15% of the stone weight). Eight stones contained no cholesterol: 4 showed an amorphous pattern and 4 were composed of calcium carbonate salts. In 7 of 8 patients with bile duct stones concomitant with gallbladder stones, results of the diffractograms of the stones from the two different sites were comparable, even in 4 cases in which the stones were macroscopically different. Neither the macroscopic appearance nor the chemical structure of the stones appeared to be influenced by the patient's sex.
AB - An x-ray diffractometric technique was used to study the crystalline composition of gallstones removed during surgery from 106 patients. Monohydrate cholesterol was found in the stones of 70 (66%) patients, either alone (33%) or in association with calcium salts (33%). The anhydrous form of cholesterol was found in the stones of 28 (26%) patients, either alone (10%) or in association with calcium salts (16%). These salts (vaterite, aragonite, and calcite) were found in 50% of cases in varying amounts (from 12% to 15% of the stone weight). Eight stones contained no cholesterol: 4 showed an amorphous pattern and 4 were composed of calcium carbonate salts. In 7 of 8 patients with bile duct stones concomitant with gallbladder stones, results of the diffractograms of the stones from the two different sites were comparable, even in 4 cases in which the stones were macroscopically different. Neither the macroscopic appearance nor the chemical structure of the stones appeared to be influenced by the patient's sex.
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UR - http://www.scopus.com/inward/citedby.url?scp=0027938186&partnerID=8YFLogxK
U2 - 10.1016/S0011-393X(05)80257-7
DO - 10.1016/S0011-393X(05)80257-7
M3 - Article
AN - SCOPUS:0027938186
VL - 55
SP - 1169
EP - 1175
JO - Current Therapeutic Research - Clinical and Experimental
JF - Current Therapeutic Research - Clinical and Experimental
SN - 0011-393X
IS - 10
ER -