Are morphology and composition of gallstones related? An x-ray diffraction study

N. Bassi, G. Del Favero, T. Meggiato, P. Scalon, S. Ghiro, M. Molin, A. Pilotto, S. Vigneri, V. Savarino, G. S. Mela, F. Di Mario

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

An x-ray diffractometric technique was used to study the crystalline composition of gallstones removed during surgery from 106 patients. Monohydrate cholesterol was found in the stones of 70 (66%) patients, either alone (33%) or in association with calcium salts (33%). The anhydrous form of cholesterol was found in the stones of 28 (26%) patients, either alone (10%) or in association with calcium salts (16%). These salts (vaterite, aragonite, and calcite) were found in 50% of cases in varying amounts (from 12% to 15% of the stone weight). Eight stones contained no cholesterol: 4 showed an amorphous pattern and 4 were composed of calcium carbonate salts. In 7 of 8 patients with bile duct stones concomitant with gallbladder stones, results of the diffractograms of the stones from the two different sites were comparable, even in 4 cases in which the stones were macroscopically different. Neither the macroscopic appearance nor the chemical structure of the stones appeared to be influenced by the patient's sex.

Original languageEnglish
Pages (from-to)1169-1175
Number of pages7
JournalCurrent Therapeutic Research
Volume55
Issue number10
DOIs
Publication statusPublished - 1994

Fingerprint

Gallstones
Calcium Carbonate
X-Rays
Salts
Cholesterol
Calcium
Bile Ducts
Gallbladder
Weights and Measures

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Bassi, N., Del Favero, G., Meggiato, T., Scalon, P., Ghiro, S., Molin, M., ... Di Mario, F. (1994). Are morphology and composition of gallstones related? An x-ray diffraction study. Current Therapeutic Research, 55(10), 1169-1175. https://doi.org/10.1016/S0011-393X(05)80257-7

Are morphology and composition of gallstones related? An x-ray diffraction study. / Bassi, N.; Del Favero, G.; Meggiato, T.; Scalon, P.; Ghiro, S.; Molin, M.; Pilotto, A.; Vigneri, S.; Savarino, V.; Mela, G. S.; Di Mario, F.

In: Current Therapeutic Research, Vol. 55, No. 10, 1994, p. 1169-1175.

Research output: Contribution to journalArticle

Bassi, N, Del Favero, G, Meggiato, T, Scalon, P, Ghiro, S, Molin, M, Pilotto, A, Vigneri, S, Savarino, V, Mela, GS & Di Mario, F 1994, 'Are morphology and composition of gallstones related? An x-ray diffraction study', Current Therapeutic Research, vol. 55, no. 10, pp. 1169-1175. https://doi.org/10.1016/S0011-393X(05)80257-7
Bassi, N. ; Del Favero, G. ; Meggiato, T. ; Scalon, P. ; Ghiro, S. ; Molin, M. ; Pilotto, A. ; Vigneri, S. ; Savarino, V. ; Mela, G. S. ; Di Mario, F. / Are morphology and composition of gallstones related? An x-ray diffraction study. In: Current Therapeutic Research. 1994 ; Vol. 55, No. 10. pp. 1169-1175.
@article{85a58680e53e449db7cc608c46c835ee,
title = "Are morphology and composition of gallstones related? An x-ray diffraction study",
abstract = "An x-ray diffractometric technique was used to study the crystalline composition of gallstones removed during surgery from 106 patients. Monohydrate cholesterol was found in the stones of 70 (66{\%}) patients, either alone (33{\%}) or in association with calcium salts (33{\%}). The anhydrous form of cholesterol was found in the stones of 28 (26{\%}) patients, either alone (10{\%}) or in association with calcium salts (16{\%}). These salts (vaterite, aragonite, and calcite) were found in 50{\%} of cases in varying amounts (from 12{\%} to 15{\%} of the stone weight). Eight stones contained no cholesterol: 4 showed an amorphous pattern and 4 were composed of calcium carbonate salts. In 7 of 8 patients with bile duct stones concomitant with gallbladder stones, results of the diffractograms of the stones from the two different sites were comparable, even in 4 cases in which the stones were macroscopically different. Neither the macroscopic appearance nor the chemical structure of the stones appeared to be influenced by the patient's sex.",
author = "N. Bassi and {Del Favero}, G. and T. Meggiato and P. Scalon and S. Ghiro and M. Molin and A. Pilotto and S. Vigneri and V. Savarino and Mela, {G. S.} and {Di Mario}, F.",
year = "1994",
doi = "10.1016/S0011-393X(05)80257-7",
language = "English",
volume = "55",
pages = "1169--1175",
journal = "Current Therapeutic Research - Clinical and Experimental",
issn = "0011-393X",
publisher = "Excerpta Medica",
number = "10",

}

TY - JOUR

T1 - Are morphology and composition of gallstones related? An x-ray diffraction study

AU - Bassi, N.

AU - Del Favero, G.

AU - Meggiato, T.

AU - Scalon, P.

AU - Ghiro, S.

AU - Molin, M.

AU - Pilotto, A.

AU - Vigneri, S.

AU - Savarino, V.

AU - Mela, G. S.

AU - Di Mario, F.

PY - 1994

Y1 - 1994

N2 - An x-ray diffractometric technique was used to study the crystalline composition of gallstones removed during surgery from 106 patients. Monohydrate cholesterol was found in the stones of 70 (66%) patients, either alone (33%) or in association with calcium salts (33%). The anhydrous form of cholesterol was found in the stones of 28 (26%) patients, either alone (10%) or in association with calcium salts (16%). These salts (vaterite, aragonite, and calcite) were found in 50% of cases in varying amounts (from 12% to 15% of the stone weight). Eight stones contained no cholesterol: 4 showed an amorphous pattern and 4 were composed of calcium carbonate salts. In 7 of 8 patients with bile duct stones concomitant with gallbladder stones, results of the diffractograms of the stones from the two different sites were comparable, even in 4 cases in which the stones were macroscopically different. Neither the macroscopic appearance nor the chemical structure of the stones appeared to be influenced by the patient's sex.

AB - An x-ray diffractometric technique was used to study the crystalline composition of gallstones removed during surgery from 106 patients. Monohydrate cholesterol was found in the stones of 70 (66%) patients, either alone (33%) or in association with calcium salts (33%). The anhydrous form of cholesterol was found in the stones of 28 (26%) patients, either alone (10%) or in association with calcium salts (16%). These salts (vaterite, aragonite, and calcite) were found in 50% of cases in varying amounts (from 12% to 15% of the stone weight). Eight stones contained no cholesterol: 4 showed an amorphous pattern and 4 were composed of calcium carbonate salts. In 7 of 8 patients with bile duct stones concomitant with gallbladder stones, results of the diffractograms of the stones from the two different sites were comparable, even in 4 cases in which the stones were macroscopically different. Neither the macroscopic appearance nor the chemical structure of the stones appeared to be influenced by the patient's sex.

UR - http://www.scopus.com/inward/record.url?scp=0027938186&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027938186&partnerID=8YFLogxK

U2 - 10.1016/S0011-393X(05)80257-7

DO - 10.1016/S0011-393X(05)80257-7

M3 - Article

AN - SCOPUS:0027938186

VL - 55

SP - 1169

EP - 1175

JO - Current Therapeutic Research - Clinical and Experimental

JF - Current Therapeutic Research - Clinical and Experimental

SN - 0011-393X

IS - 10

ER -