Are nongenetic triggers for dystonia type-specific? A study exploring scoliosis in blepharospasm

Davide Martino; Giovanni Defazio; Giovanni Abbruzzese; Roberta Marchese; Giovanni Fabbrini; Venturino Decembrino; Alfredo Berardelli

doi:10.1002/mds.21322

Are nongenetic triggers for dystonia type-specific? A study exploring scoliosis in blepharospasm

Davide Martino, Giovanni Defazio, Giovanni Abbruzzese, Roberta Marchese, Giovanni Fabbrini, Venturino Decembrino, Alfredo Berardelli

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Abstract

We previously observed that diseases of the anterior ocular segment predispose to primary blepharospasm, but not to other focal dystonias. In this multicenter study, we tested whether prior scoliosis, which increases the risk of developing cervical dystonia, is also a predisposing factor to blepharospasm. The frequency of scoliosis did not differ between blepharospasm patients and controls. This finding supports the hypothesis that environmental risk factors may be specific for a single form of adult-onset dystonia.

Original language	English
Pages (from-to)	576-578
Number of pages	3
Journal	Movement Disorders
Volume	22
Issue number	4
DOIs	https://doi.org/10.1002/mds.21322
Publication status	Published - Mar 15 2007

Keywords

Blepharospasm
Dystonia
Risk factors
Scoliosis

ASJC Scopus subject areas

Clinical Neurology
Neuroscience(all)

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10.1002/mds.21322

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abstract = "We previously observed that diseases of the anterior ocular segment predispose to primary blepharospasm, but not to other focal dystonias. In this multicenter study, we tested whether prior scoliosis, which increases the risk of developing cervical dystonia, is also a predisposing factor to blepharospasm. The frequency of scoliosis did not differ between blepharospasm patients and controls. This finding supports the hypothesis that environmental risk factors may be specific for a single form of adult-onset dystonia.",

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AU - Martino, Davide

AU - Defazio, Giovanni

AU - Abbruzzese, Giovanni

AU - Marchese, Roberta

AU - Fabbrini, Giovanni

AU - Decembrino, Venturino

AU - Berardelli, Alfredo

PY - 2007/3/15

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N2 - We previously observed that diseases of the anterior ocular segment predispose to primary blepharospasm, but not to other focal dystonias. In this multicenter study, we tested whether prior scoliosis, which increases the risk of developing cervical dystonia, is also a predisposing factor to blepharospasm. The frequency of scoliosis did not differ between blepharospasm patients and controls. This finding supports the hypothesis that environmental risk factors may be specific for a single form of adult-onset dystonia.

AB - We previously observed that diseases of the anterior ocular segment predispose to primary blepharospasm, but not to other focal dystonias. In this multicenter study, we tested whether prior scoliosis, which increases the risk of developing cervical dystonia, is also a predisposing factor to blepharospasm. The frequency of scoliosis did not differ between blepharospasm patients and controls. This finding supports the hypothesis that environmental risk factors may be specific for a single form of adult-onset dystonia.

KW - Blepharospasm

KW - Dystonia

KW - Risk factors

KW - Scoliosis

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Are nongenetic triggers for dystonia type-specific? A study exploring scoliosis in blepharospasm

Abstract

Keywords

ASJC Scopus subject areas

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