Are pitch and roll compensations required in all pathologies? A data analysis of 2945 fractions

Pietro Mancosu, Giacomo Reggiori, Anna Gaudino, Francesca Lobefalo, Lucia Paganini, Valentina Palumbo, Antonella Stravato, Stefano Tomatis, Marta Scorsetti

Research output: Contribution to journalArticlepeer-review


Objective: New linear accelerators can be equipped with a 6D robotic couch, providing two additional rotational motion axes: pitch and roll. These shifts in kilo voltage-cone beam CT (kV-CBCT) image-guided radiotherapy (IGRT) were evaluated over the first 6 months of usage of a 6D robotic couch-top, ranking the treatment sites for which the two compensations are larger for patient set-up. Methods: The couch compensations of 2945 fractions for 376 consecutive patients treated on the PerfectPitch™ 6D couch (Varian® Medical Systems, Palo Alto, CA) were analysed. Among these patients, 169 were treated for brain, 111 for lung, 54 for liver, 26 for pancreas and 16 for prostate tumours. During the set-up, patient anatomy from planning CT was aligned to kV-CBCT, and 6D movements were executed. Information related to pitch and roll were extracted by proper querying of the Microsoft® SQL server (Microsoft Corporation, Redmond, WA) ARIA database (Varian Medical Systems). Mean values and standard deviations were calculated for all sites. Kolmogorov- Smirnov (KS) test was performed. Results: Considering all the data, mean pitch and roll adjustments were 20.10°60.92° and 0.12°60.96°, respectively; mean absolute values for both adjustments were 0.58°60.69° and 0.69°60.72°, respectively. Brain treatments showed the highest mean absolute values for pitch and roll rotations (0.73°60.69° and 0.80°60.78°, respectively); the lowest values of 0.36°60.47° and 0.49°60.58° were found for pancreas. KS test was significant for brain vs liver, pancreas and prostate. Collective corrections (pitch1 roll) .0.5°, .1.0° and .2.0° were observed in, respectively, 79.8%, 61.0% and 29.1% for brain and 56.7%, 39.4% and 6.7% for pancreas. Conclusion: Adjustments in all six dimensions, including unconventional pitch and roll rotations, improve the patient set-up in all treatment sites. The greatest improvement was observed for patients with brain tumours. Advances in knowledge: To our knowledge, this is the first systematic evaluation of the clinical efficacy of a 6D Robotic couch-top in CBCT IGRT over different tumour regions.

Original languageEnglish
JournalBritish Journal of Radiology
Issue number1055
Publication statusPublished - 2015

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Medicine(all)


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