Are subjective cognitive complaints a risk factor for dementia

Roberto Gallassi, Federico Oppi, Roberto Poda, Simona Scortichini, Michelangelo Stanzani Maserati, Gianfranco Marano, Luisa Sambati

Research output: Contribution to journalArticlepeer-review


The objective is to evaluate the prognosis of subjective cognitive complaints (SCC) patients during 4- year follow-up. A prospective study on 92 SCC patients investigating their cognitive, affective and behavioural aspects. SCC patients were classified as having no objective cognitive impairment (NOCI), mild cognitive impairment (MCI), or subtypes of MCI. Results: 43 patients were found to have NOCI and 49 MCI. During the follow-up, 45.5% of NOCI patients remained unchanged, 13.9% were diagnosed as MCI and only one progressed to dementia. Of the MCI patients, 32.3% remained stable, 18.4% became demented and 4% reverted to NOCI. Visual attention, behavioural memory, long-term verbal memory, apathy and caregiver distress, provided independent predictors of progression to dementia.

Original languageEnglish
Pages (from-to)327-336
Number of pages10
JournalNeurological Sciences
Issue number3
Publication statusPublished - Jun 2010


  • Memory
  • Mild cognitive impairment
  • Neuropsychological tests
  • Subjective cognitive complaints

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health
  • Dermatology
  • Medicine(all)


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