TY - JOUR
T1 - Aripiprazole-Induced Oculogyric Crisis
T2 - A Pediatric Case Series and A Brief Narrative Review
AU - Bernardo, Pia
AU - Rubino, Alfonso
AU - Santoro, Claudia
AU - Bravaccio, Carmela
AU - Pozzi, Marco
AU - Pisano, Simone
N1 - Funding Information:
Funding: This work was supported by the Italian Ministry of Health (Ricerca Corrente, to MP) which is gratefully acknowledged. The funding public institution had no role in any part of the work.
Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2022/1
Y1 - 2022/1
N2 - Oculogyric crisis (OGC) represent an unusual type of dystonic movement disorder, usually reported as an adverse event of antipsychotic drugs, with acute or tardive onset, likely due to a functional disruption of dopaminergic neurotransmission. It is seldom reported in children with aripiprazole, an atypical antipsychotic commonly used in youths. In this manuscript, we report on a case series of three pediatric patients and provide a brief narrative review of the literature, in order to increase the awareness of clinicians and to foster future research in this area.
AB - Oculogyric crisis (OGC) represent an unusual type of dystonic movement disorder, usually reported as an adverse event of antipsychotic drugs, with acute or tardive onset, likely due to a functional disruption of dopaminergic neurotransmission. It is seldom reported in children with aripiprazole, an atypical antipsychotic commonly used in youths. In this manuscript, we report on a case series of three pediatric patients and provide a brief narrative review of the literature, in order to increase the awareness of clinicians and to foster future research in this area.
KW - Aripiprazole
KW - Extrapyramidal effects
KW - Oculogyric crisis
KW - Pediatric
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U2 - 10.3390/children9010022
DO - 10.3390/children9010022
M3 - Article
AN - SCOPUS:85122020633
VL - 9
JO - Child.
JF - Child.
SN - 2227-9067
IS - 1
M1 - 22
ER -