Arming CTLs against immunosuppressors

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Cell therapy efficacy after organ transplantation is hampered by the detrimental effects of pharmacologic immunosuppression on T-cell expansion and function. In this issue of Blood, 2 independent groups describe genetic engineering of ex vivo expanded EBV-CTLs to induce calcineurin-inhibitor resistance.

Original languageEnglish
Pages (from-to)4759-4760
Number of pages2
JournalBlood
Volume114
Issue number23
DOIs
Publication statusPublished - Nov 26 2009

Fingerprint

Transplantation (surgical)
Genetic engineering
Genetic Engineering
T-cells
Organ Transplantation
Cell- and Tissue-Based Therapy
Human Herpesvirus 4
Immunosuppression
Blood
T-Lymphocytes
Calcineurin Inhibitors

ASJC Scopus subject areas

  • Biochemistry
  • Cell Biology
  • Immunology
  • Hematology

Cite this

Arming CTLs against immunosuppressors. / Comoli, Patrizia.

In: Blood, Vol. 114, No. 23, 26.11.2009, p. 4759-4760.

Research output: Contribution to journalArticle

Comoli, Patrizia. / Arming CTLs against immunosuppressors. In: Blood. 2009 ; Vol. 114, No. 23. pp. 4759-4760.
@article{f209c271488b468d98e53474d13da90d,
title = "Arming CTLs against immunosuppressors",
abstract = "Cell therapy efficacy after organ transplantation is hampered by the detrimental effects of pharmacologic immunosuppression on T-cell expansion and function. In this issue of Blood, 2 independent groups describe genetic engineering of ex vivo expanded EBV-CTLs to induce calcineurin-inhibitor resistance.",
author = "Patrizia Comoli",
year = "2009",
month = "11",
day = "26",
doi = "10.1182/blood-2009-09-244905",
language = "English",
volume = "114",
pages = "4759--4760",
journal = "Blood",
issn = "0006-4971",
publisher = "American Society of Hematology",
number = "23",

}

TY - JOUR

T1 - Arming CTLs against immunosuppressors

AU - Comoli, Patrizia

PY - 2009/11/26

Y1 - 2009/11/26

N2 - Cell therapy efficacy after organ transplantation is hampered by the detrimental effects of pharmacologic immunosuppression on T-cell expansion and function. In this issue of Blood, 2 independent groups describe genetic engineering of ex vivo expanded EBV-CTLs to induce calcineurin-inhibitor resistance.

AB - Cell therapy efficacy after organ transplantation is hampered by the detrimental effects of pharmacologic immunosuppression on T-cell expansion and function. In this issue of Blood, 2 independent groups describe genetic engineering of ex vivo expanded EBV-CTLs to induce calcineurin-inhibitor resistance.

UR - http://www.scopus.com/inward/record.url?scp=77950428412&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77950428412&partnerID=8YFLogxK

U2 - 10.1182/blood-2009-09-244905

DO - 10.1182/blood-2009-09-244905

M3 - Article

VL - 114

SP - 4759

EP - 4760

JO - Blood

JF - Blood

SN - 0006-4971

IS - 23

ER -