Arterial alterations in hypertension

Gino Seravalle; Guido Grassi; Giuseppe Mancia

doi:10.1007/978-3-319-14556-3_20

Arterial alterations in hypertension

Gino Seravalle, Guido Grassi, Giuseppe Mancia

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Several metabolic, humoral, local, and neural influences contribute to the homeostatic control of the cardiovascular system. All these factors physiologically interact with each other and participate in the regulation of cardiac as well as vascular function. Both endothelial and sympathetic functions seem to be the main important regulatory mechanisms involved in maintaining the homeostatic balance and participating in the cardiovascular responses to environmental needs. The alterations of these mechanisms represent the key factor for the cardiovascular modifications typical of several clinical conditions, such as heart, kidney, lung, and liver diseases as well as obesity and diabetes and represent the target for non-pharmacologic and pharmacologic interventions.

Original language	English
Title of host publication	Arterial Disorders: Definition, Clinical Manifestations, Mechanisms and Therapeutic Approaches
Publisher	Springer International Publishing
Pages	285-297
Number of pages	13
ISBN (Print)	9783319145563, 9783319145556
DOIs	https://doi.org/10.1007/978-3-319-14556-3_20
Publication status	Published - Jan 1 2015

Keywords

Cardiovascular risk
Hypertension
Large arteries
Microcirculation
Target organ damage

ASJC Scopus subject areas

Medicine(all)

Access to Document

10.1007/978-3-319-14556-3_20

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