Arterial endothelial dysfunction and idiopathic deep venous thrombosis

Gianluigi Mazzoccoli, M. Grilli, F. Ferrandino, M. Copetti, A. Fontana, F. Pellegrini, M. P. Dagostino, A. De Cata, G. Vendemiale

Research output: Contribution to journalArticlepeer-review


Recent epidemiological studies have highlighted higher risk of subsequent development of atherosclerotic disease in patients with deep venous thrombosis (DVT). We evaluated the Flow Mediated Dilation (FMD) looking for arterial endothelial dysfunction, predictive for future ischaemic cardiovascular events, in patients with idiopathic DVT. FMD was measured in the brachial artery in 60 subjects with idiopathic DVT (age 60.1±17.4) and in 60 subjects without idiopathic DVT (age 61.2±15.1), with a similar cardiovascular risk factor profile. DVT patients showed lower FMD (6.78%±5.53% vs 10.88±3.31%, p

Original languageEnglish
Pages (from-to)565-573
Number of pages9
JournalJournal of Biological Regulators and Homeostatic Agents
Issue number4
Publication statusPublished - Oct 2011


  • Atherosclerosis
  • Endothelial dysfunction
  • Flow mediated dilation
  • Venous thrombosis

ASJC Scopus subject areas

  • Oncology
  • Endocrinology, Diabetes and Metabolism
  • Physiology (medical)
  • Immunology and Allergy
  • Immunology
  • Endocrinology
  • Physiology
  • Cancer Research


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