Arterial endothelial dysfunction and idiopathic deep venous thrombosis

Gianluigi Mazzoccoli; M. Grilli; F. Ferrandino; M. Copetti; A. Fontana; F. Pellegrini; M. P. Dagostino; A. De Cata; G. Vendemiale

Arterial endothelial dysfunction and idiopathic deep venous thrombosis

Gianluigi Mazzoccoli, M. Grilli, F. Ferrandino, M. Copetti, A. Fontana, F. Pellegrini, M. P. Dagostino, A. De Cata, G. Vendemiale

IRCCS Casa Sollievo della Sofferenza

Research output: Contribution to journal › Article › peer-review

Abstract

Recent epidemiological studies have highlighted higher risk of subsequent development of atherosclerotic disease in patients with deep venous thrombosis (DVT). We evaluated the Flow Mediated Dilation (FMD) looking for arterial endothelial dysfunction, predictive for future ischaemic cardiovascular events, in patients with idiopathic DVT. FMD was measured in the brachial artery in 60 subjects with idiopathic DVT (age 60.1±17.4) and in 60 subjects without idiopathic DVT (age 61.2±15.1), with a similar cardiovascular risk factor profile. DVT patients showed lower FMD (6.78%±5.53% vs 10.88±3.31%, p

Original language	English
Pages (from-to)	565-573
Number of pages	9
Journal	Journal of Biological Regulators and Homeostatic Agents
Volume	25
Issue number	4
Publication status	Published - Oct 2011

Keywords

Atherosclerosis
Endothelial dysfunction
Flow mediated dilation
Venous thrombosis

ASJC Scopus subject areas

Oncology
Endocrinology, Diabetes and Metabolism
Physiology (medical)
Immunology and Allergy
Immunology
Endocrinology
Physiology
Cancer Research

Cite this

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AU - Mazzoccoli, Gianluigi

AU - Grilli, M.

AU - Ferrandino, F.

AU - Copetti, M.

AU - Fontana, A.

AU - Pellegrini, F.

AU - Dagostino, M. P.

AU - De Cata, A.

AU - Vendemiale, G.

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AB - Recent epidemiological studies have highlighted higher risk of subsequent development of atherosclerotic disease in patients with deep venous thrombosis (DVT). We evaluated the Flow Mediated Dilation (FMD) looking for arterial endothelial dysfunction, predictive for future ischaemic cardiovascular events, in patients with idiopathic DVT. FMD was measured in the brachial artery in 60 subjects with idiopathic DVT (age 60.1±17.4) and in 60 subjects without idiopathic DVT (age 61.2±15.1), with a similar cardiovascular risk factor profile. DVT patients showed lower FMD (6.78%±5.53% vs 10.88±3.31%, p

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Arterial endothelial dysfunction and idiopathic deep venous thrombosis

Abstract

Keywords

ASJC Scopus subject areas

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