Arterial stiffness and amplification in the very old

Athanase Benetos, Ghassan Watfa, Paolo Salvi, Patrick Lacolley

Research output: Chapter in Book/Report/Conference proceedingChapter


The progressive aging of the population has had a profound impact on the increase in the prevalence and incidence of diseases associated with aging. Arterial aging (as occurs with atherothrombosis, systolic hypertension, heart failure, and vascular dementia) is one of the primary causes of loss of autonomy, morbidity, and mortality in the elderly. Arterial stiffness, expressed as systolic hypertension, is the typical manifestation of arterial aging. In the past, increases in systolic and pulse pressure (PP) were considered part of the aging process and thus did not require therapeutic intervention. However, although arterial stiffening is common, older subjects with increased arterial stiffness have higher cardiovascular morbidity and mortality. It is therefore important to assess arterial stiffness and its consequences in the aging process. Actually, using methods that can analyze the BP curve and/or directly measure arterial elastic properties may represent a very interesting approach to assess the clinical and hemodynamic consequences of the arterial aging.

Original languageEnglish
Title of host publicationBlood Pressure and Arterial Wall Mechanics in Cardiovascular Diseases
PublisherSpringer-Verlag London Ltd
Number of pages9
ISBN (Print)9781447151982, 1447151984, 9781447151975
Publication statusPublished - Mar 1 2014


  • Aging
  • Aorta
  • Arterial stiffness
  • Cardiovascular
  • Dementia
  • Elderly
  • Hypertension
  • Morbidity
  • Mortality

ASJC Scopus subject areas

  • Medicine(all)


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