Arterial stiffness and left ventricular performance in elderly patients with persistent atrial fibrillation

Stefano Fumagalli; Marta Migliorini; Simone Pupo; Irene Marozzi; Serena Boni; Alessandra Scardia; Alessandro Masi; Anna T Roberts; Luigi Padeletti; Niccolò Marchionni

doi:10.1007/s40520-018-0935-8

Arterial stiffness and left ventricular performance in elderly patients with persistent atrial fibrillation

Stefano Fumagalli, Marta Migliorini, Simone Pupo, Irene Marozzi, Serena Boni, Alessandra Scardia, Alessandro Masi, Anna T Roberts, Luigi Padeletti, Niccolò Marchionni

IRCCS Multimedica

Research output: Contribution to journal › Article › peer-review

Abstract

BACKGROUND: The prevalence of atrial fibrillation (AF) and arterial stiffness (AS) increases with age.

AIMS: To evaluate if AS is correlated to longitudinal strain (LS), a marker of left ventricular (LV) function, in elderly AF patients with preserved ejection fraction (EF) undergoing external cardioversion.

METHODS: AS was measured using the cardio-ankle vascular index (CAVI), LS was calculated from echocardiographic data of three consecutive cardiac cycles.

RESULTS: We enrolled 38 patients (age 76 ± 8 years; men 60.5%; EF 65 ± 7%). LS and CAVI were, respectively, - 17.7 ± 3.7% and 9.7 ± 1.3. Multivariate analysis showed that LV performance was inversely related to height (p < 0.001) and to the presence of AF-related symptoms (p = 0.008). LS grew with increasing values of CAVI (p = 0.038).

CONCLUSIONS: In elderly AF patients with preserved systolic function, LV performance is directly associated with AS. This link could influence atrium remodeling and the incidence of arrhythmia relapse.

Original language	English
Pages (from-to)	1403-1408
Number of pages	6
Journal	Aging clinical and experimental research
Volume	30
Issue number	11
DOIs	https://doi.org/10.1007/s40520-018-0935-8
Publication status	Published - Nov 2018

Keywords

Aged
Aged, 80 and over
Atrial Fibrillation/complications
Echocardiography
Electric Countershock
Female
Humans
Male
Multivariate Analysis
Vascular Stiffness
Ventricular Function, Left

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10.1007/s40520-018-0935-8

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title = "Arterial stiffness and left ventricular performance in elderly patients with persistent atrial fibrillation",

abstract = "BACKGROUND: The prevalence of atrial fibrillation (AF) and arterial stiffness (AS) increases with age.AIMS: To evaluate if AS is correlated to longitudinal strain (LS), a marker of left ventricular (LV) function, in elderly AF patients with preserved ejection fraction (EF) undergoing external cardioversion.METHODS: AS was measured using the cardio-ankle vascular index (CAVI), LS was calculated from echocardiographic data of three consecutive cardiac cycles.RESULTS: We enrolled 38 patients (age 76 ± 8 years; men 60.5%; EF 65 ± 7%). LS and CAVI were, respectively, - 17.7 ± 3.7% and 9.7 ± 1.3. Multivariate analysis showed that LV performance was inversely related to height (p < 0.001) and to the presence of AF-related symptoms (p = 0.008). LS grew with increasing values of CAVI (p = 0.038).CONCLUSIONS: In elderly AF patients with preserved systolic function, LV performance is directly associated with AS. This link could influence atrium remodeling and the incidence of arrhythmia relapse.",

keywords = "Aged, Aged, 80 and over, Atrial Fibrillation/complications, Echocardiography, Electric Countershock, Female, Humans, Male, Multivariate Analysis, Vascular Stiffness, Ventricular Function, Left",

author = "Stefano Fumagalli and Marta Migliorini and Simone Pupo and Irene Marozzi and Serena Boni and Alessandra Scardia and Alessandro Masi and Roberts, {Anna T} and Luigi Padeletti and Niccol{\`o} Marchionni",

year = "2018",

month = nov,

doi = "10.1007/s40520-018-0935-8",

language = "English",

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pages = "1403--1408",

journal = "Aging clinical and experimental research",

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TY - JOUR

T1 - Arterial stiffness and left ventricular performance in elderly patients with persistent atrial fibrillation

AU - Fumagalli, Stefano

AU - Migliorini, Marta

AU - Pupo, Simone

AU - Marozzi, Irene

AU - Boni, Serena

AU - Scardia, Alessandra

AU - Masi, Alessandro

AU - Roberts, Anna T

AU - Padeletti, Luigi

AU - Marchionni, Niccolò

PY - 2018/11

Y1 - 2018/11

N2 - BACKGROUND: The prevalence of atrial fibrillation (AF) and arterial stiffness (AS) increases with age.AIMS: To evaluate if AS is correlated to longitudinal strain (LS), a marker of left ventricular (LV) function, in elderly AF patients with preserved ejection fraction (EF) undergoing external cardioversion.METHODS: AS was measured using the cardio-ankle vascular index (CAVI), LS was calculated from echocardiographic data of three consecutive cardiac cycles.RESULTS: We enrolled 38 patients (age 76 ± 8 years; men 60.5%; EF 65 ± 7%). LS and CAVI were, respectively, - 17.7 ± 3.7% and 9.7 ± 1.3. Multivariate analysis showed that LV performance was inversely related to height (p < 0.001) and to the presence of AF-related symptoms (p = 0.008). LS grew with increasing values of CAVI (p = 0.038).CONCLUSIONS: In elderly AF patients with preserved systolic function, LV performance is directly associated with AS. This link could influence atrium remodeling and the incidence of arrhythmia relapse.

AB - BACKGROUND: The prevalence of atrial fibrillation (AF) and arterial stiffness (AS) increases with age.AIMS: To evaluate if AS is correlated to longitudinal strain (LS), a marker of left ventricular (LV) function, in elderly AF patients with preserved ejection fraction (EF) undergoing external cardioversion.METHODS: AS was measured using the cardio-ankle vascular index (CAVI), LS was calculated from echocardiographic data of three consecutive cardiac cycles.RESULTS: We enrolled 38 patients (age 76 ± 8 years; men 60.5%; EF 65 ± 7%). LS and CAVI were, respectively, - 17.7 ± 3.7% and 9.7 ± 1.3. Multivariate analysis showed that LV performance was inversely related to height (p < 0.001) and to the presence of AF-related symptoms (p = 0.008). LS grew with increasing values of CAVI (p = 0.038).CONCLUSIONS: In elderly AF patients with preserved systolic function, LV performance is directly associated with AS. This link could influence atrium remodeling and the incidence of arrhythmia relapse.

KW - Aged

KW - Aged, 80 and over

KW - Atrial Fibrillation/complications

KW - Echocardiography

KW - Electric Countershock

KW - Female

KW - Humans

KW - Male

KW - Multivariate Analysis

KW - Vascular Stiffness

KW - Ventricular Function, Left

U2 - 10.1007/s40520-018-0935-8

DO - 10.1007/s40520-018-0935-8

M3 - Article

C2 - 29569118

VL - 30

SP - 1403

EP - 1408

JO - Aging clinical and experimental research

JF - Aging clinical and experimental research

SN - 1594-0667

IS - 11

ER -

Arterial stiffness and left ventricular performance in elderly patients with persistent atrial fibrillation

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Keywords

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