Arterial stiffness and left ventricular performance in elderly patients with persistent atrial fibrillation

Stefano Fumagalli; Marta Migliorini; Simone Pupo; Irene Marozzi; Serena Boni; Alessandra Scardia; Alessandro Masi; Anna T Roberts; Luigi Padeletti; Niccolò Marchionni

doi:10.1007/s40520-018-0935-8

Arterial stiffness and left ventricular performance in elderly patients with persistent atrial fibrillation

Stefano Fumagalli, Marta Migliorini, Simone Pupo, Irene Marozzi, Serena Boni, Alessandra Scardia, Alessandro Masi, Anna T Roberts, Luigi Padeletti, Niccolò Marchionni

IRCCS Multimedica

Research output: Contribution to journal › Article

Abstract

BACKGROUND: The prevalence of atrial fibrillation (AF) and arterial stiffness (AS) increases with age.

AIMS: To evaluate if AS is correlated to longitudinal strain (LS), a marker of left ventricular (LV) function, in elderly AF patients with preserved ejection fraction (EF) undergoing external cardioversion.

METHODS: AS was measured using the cardio-ankle vascular index (CAVI), LS was calculated from echocardiographic data of three consecutive cardiac cycles.

RESULTS: We enrolled 38 patients (age 76 ± 8 years; men 60.5%; EF 65 ± 7%). LS and CAVI were, respectively, - 17.7 ± 3.7% and 9.7 ± 1.3. Multivariate analysis showed that LV performance was inversely related to height (p < 0.001) and to the presence of AF-related symptoms (p = 0.008). LS grew with increasing values of CAVI (p = 0.038).

CONCLUSIONS: In elderly AF patients with preserved systolic function, LV performance is directly associated with AS. This link could influence atrium remodeling and the incidence of arrhythmia relapse.

Original language	English
Pages (from-to)	1403-1408
Number of pages	6
Journal	Aging clinical and experimental research
Volume	30
Issue number	11
DOIs	https://doi.org/10.1007/s40520-018-0935-8
Publication status	Published - Nov 2018

Keywords

Aged
Aged, 80 and over
Atrial Fibrillation/complications
Echocardiography
Electric Countershock
Female
Humans
Male
Multivariate Analysis
Vascular Stiffness
Ventricular Function, Left

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Fumagalli, S., Migliorini, M., Pupo, S., Marozzi, I., Boni, S., Scardia, A., Masi, A., Roberts, A. T., Padeletti, L., & Marchionni, N. (2018). Arterial stiffness and left ventricular performance in elderly patients with persistent atrial fibrillation. Aging clinical and experimental research, 30(11), 1403-1408. https://doi.org/10.1007/s40520-018-0935-8

Arterial stiffness and left ventricular performance in elderly patients with persistent atrial fibrillation. / Fumagalli, Stefano; Migliorini, Marta; Pupo, Simone; Marozzi, Irene; Boni, Serena; Scardia, Alessandra; Masi, Alessandro; Roberts, Anna T; Padeletti, Luigi; Marchionni, Niccolò.

In: Aging clinical and experimental research, Vol. 30, No. 11, 11.2018, p. 1403-1408.

Research output: Contribution to journal › Article

Fumagalli, Stefano ; Migliorini, Marta ; Pupo, Simone ; Marozzi, Irene ; Boni, Serena ; Scardia, Alessandra ; Masi, Alessandro ; Roberts, Anna T ; Padeletti, Luigi ; Marchionni, Niccolò. / Arterial stiffness and left ventricular performance in elderly patients with persistent atrial fibrillation. In: Aging clinical and experimental research. 2018 ; Vol. 30, No. 11. pp. 1403-1408.

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abstract = "BACKGROUND: The prevalence of atrial fibrillation (AF) and arterial stiffness (AS) increases with age.AIMS: To evaluate if AS is correlated to longitudinal strain (LS), a marker of left ventricular (LV) function, in elderly AF patients with preserved ejection fraction (EF) undergoing external cardioversion.METHODS: AS was measured using the cardio-ankle vascular index (CAVI), LS was calculated from echocardiographic data of three consecutive cardiac cycles.RESULTS: We enrolled 38 patients (age 76 ± 8 years; men 60.5%; EF 65 ± 7%). LS and CAVI were, respectively, - 17.7 ± 3.7% and 9.7 ± 1.3. Multivariate analysis showed that LV performance was inversely related to height (p < 0.001) and to the presence of AF-related symptoms (p = 0.008). LS grew with increasing values of CAVI (p = 0.038).CONCLUSIONS: In elderly AF patients with preserved systolic function, LV performance is directly associated with AS. This link could influence atrium remodeling and the incidence of arrhythmia relapse.",

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AU - Pupo, Simone

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AU - Boni, Serena

AU - Scardia, Alessandra

AU - Masi, Alessandro

AU - Roberts, Anna T

AU - Padeletti, Luigi

AU - Marchionni, Niccolò

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N2 - BACKGROUND: The prevalence of atrial fibrillation (AF) and arterial stiffness (AS) increases with age.AIMS: To evaluate if AS is correlated to longitudinal strain (LS), a marker of left ventricular (LV) function, in elderly AF patients with preserved ejection fraction (EF) undergoing external cardioversion.METHODS: AS was measured using the cardio-ankle vascular index (CAVI), LS was calculated from echocardiographic data of three consecutive cardiac cycles.RESULTS: We enrolled 38 patients (age 76 ± 8 years; men 60.5%; EF 65 ± 7%). LS and CAVI were, respectively, - 17.7 ± 3.7% and 9.7 ± 1.3. Multivariate analysis showed that LV performance was inversely related to height (p < 0.001) and to the presence of AF-related symptoms (p = 0.008). LS grew with increasing values of CAVI (p = 0.038).CONCLUSIONS: In elderly AF patients with preserved systolic function, LV performance is directly associated with AS. This link could influence atrium remodeling and the incidence of arrhythmia relapse.

AB - BACKGROUND: The prevalence of atrial fibrillation (AF) and arterial stiffness (AS) increases with age.AIMS: To evaluate if AS is correlated to longitudinal strain (LS), a marker of left ventricular (LV) function, in elderly AF patients with preserved ejection fraction (EF) undergoing external cardioversion.METHODS: AS was measured using the cardio-ankle vascular index (CAVI), LS was calculated from echocardiographic data of three consecutive cardiac cycles.RESULTS: We enrolled 38 patients (age 76 ± 8 years; men 60.5%; EF 65 ± 7%). LS and CAVI were, respectively, - 17.7 ± 3.7% and 9.7 ± 1.3. Multivariate analysis showed that LV performance was inversely related to height (p < 0.001) and to the presence of AF-related symptoms (p = 0.008). LS grew with increasing values of CAVI (p = 0.038).CONCLUSIONS: In elderly AF patients with preserved systolic function, LV performance is directly associated with AS. This link could influence atrium remodeling and the incidence of arrhythmia relapse.

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KW - Multivariate Analysis

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KW - Ventricular Function, Left

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