Abstract
Increased arterial stiffness is emerging as a useful marker of cardiovascular damage. A growing body of evidence suggests that the stiffening of the conduit arteries is linearly associated with poor survival in the general population and high-risk population such as Chronic Kidney Disease (CKD) patients. Indeed, the loss of the elastic properties of conduit arteries induces an increase in the central pulse pressure and cardiac workload leading to left ventricular hypertrophy and reduced coronary and capillary perfusion. Notably, all these changes are independent of mean blood pressure and other established cardiovascular risk factors. Though, evidence is still inconclusive, some preliminary data suggest that arterial stiffness and central blood pressure evaluation can be of use for risk stratification and treatment individualization. We herein summarize the current evidence supporting the usefulness of arterial stiffness assessment for CKD patients' management.
| Original language | English |
|---|---|
| Pages (from-to) | 244-249 |
| Number of pages | 6 |
| Journal | Current Hypertension Reviews |
| Volume | 8 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 2012 |
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Keywords
- Arterial stiffness
- Atherosclerosis
- Chronic kidney disease
- Pulse wave velocity
- Vascular calcification
ASJC Scopus subject areas
- Internal Medicine
Cite this
Arterial stiffness, pulse wave analyses : What can't blood pressure tell you in Chronic Kidney Disease. / Bellasi, Antonio; Salvi, Paolo; Papagni, Sergio; Ferramosca, Emiliana; Ratti, Carlo; Russo, Domenico; Di Iorio, Biagio.
In: Current Hypertension Reviews, Vol. 8, No. 4, 2012, p. 244-249.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Arterial stiffness, pulse wave analyses
T2 - What can't blood pressure tell you in Chronic Kidney Disease
AU - Bellasi, Antonio
AU - Salvi, Paolo
AU - Papagni, Sergio
AU - Ferramosca, Emiliana
AU - Ratti, Carlo
AU - Russo, Domenico
AU - Di Iorio, Biagio
PY - 2012
Y1 - 2012
N2 - Increased arterial stiffness is emerging as a useful marker of cardiovascular damage. A growing body of evidence suggests that the stiffening of the conduit arteries is linearly associated with poor survival in the general population and high-risk population such as Chronic Kidney Disease (CKD) patients. Indeed, the loss of the elastic properties of conduit arteries induces an increase in the central pulse pressure and cardiac workload leading to left ventricular hypertrophy and reduced coronary and capillary perfusion. Notably, all these changes are independent of mean blood pressure and other established cardiovascular risk factors. Though, evidence is still inconclusive, some preliminary data suggest that arterial stiffness and central blood pressure evaluation can be of use for risk stratification and treatment individualization. We herein summarize the current evidence supporting the usefulness of arterial stiffness assessment for CKD patients' management.
AB - Increased arterial stiffness is emerging as a useful marker of cardiovascular damage. A growing body of evidence suggests that the stiffening of the conduit arteries is linearly associated with poor survival in the general population and high-risk population such as Chronic Kidney Disease (CKD) patients. Indeed, the loss of the elastic properties of conduit arteries induces an increase in the central pulse pressure and cardiac workload leading to left ventricular hypertrophy and reduced coronary and capillary perfusion. Notably, all these changes are independent of mean blood pressure and other established cardiovascular risk factors. Though, evidence is still inconclusive, some preliminary data suggest that arterial stiffness and central blood pressure evaluation can be of use for risk stratification and treatment individualization. We herein summarize the current evidence supporting the usefulness of arterial stiffness assessment for CKD patients' management.
KW - Arterial stiffness
KW - Atherosclerosis
KW - Chronic kidney disease
KW - Pulse wave velocity
KW - Vascular calcification
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UR - http://www.scopus.com/inward/citedby.url?scp=84873123753&partnerID=8YFLogxK
U2 - 10.2174/157340212804546152
DO - 10.2174/157340212804546152
M3 - Article
VL - 8
SP - 244
EP - 249
JO - Current Hypertension Reviews
JF - Current Hypertension Reviews
SN - 1573-4021
IS - 4
ER -