Quanto aumenta il rischio di sviluppare un tumore nei bambini esposti a esame TC?

Translated title of the contribution: As it increases the risk of developing cancer in children exposed to CT?

Matteo Bruschettini, Luca A. Ramenghi

Research output: Contribution to journalArticlepeer-review

Abstract

What is the excess risk of cancer after CT scan in children? Recently The Lancet published a study in which a positive association between radiation dose from CT scan and leukemia and brain tumor was found. Data came from this retrospective cohort study in UK of almost 180,000 patients younger than 22 years of age without previous cancer diagnoses who were first examined with CT in some National Health Service (NHS) centres. Follow-up for leukemia began 2 years after the first CT and for brain cancer 5 years after the first CT in order to avoid inclusion of CT scans related to cancer diagnosis. A positive association between radiation dose from CT scans and leukemia and brain cancer was found. Compared with patients who received a dose of less than 5 mGy, leukemia incidence was about three times higher in patients who received a cumulative dose of at least 30 mGy and for brain cancer in patients who received a dose of 50-74 mGy. Since these cancers are relatively rare, the cumulative absolute risks are small. Nevertheless, although clinical benefits should outweigh the small absolute risks, radiation doses from CT scans ought to be kept as low as possible and alternative procedures, which do not involve ionizing radiation, should be taken in consideration if appropriate.

Translated title of the contributionAs it increases the risk of developing cancer in children exposed to CT?
Original languageItalian
Pages (from-to)68-70
Number of pages3
JournalQuaderni ACP
Volume20
Issue number2
Publication statusPublished - 2013

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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