Various features of tubular function were studied in 14 cases of renal transplant. Satisfactory recovery of function in the regulation of acid base balance was observed within 10 days of the restoration of diuresis. Osmolar and free water clearance showed a gradual increase and negativization respectively over the same period. All of 6 patients subjected to acute acidifying load for over a year from the transplant and so presumably free of intraoperative ischemic lesions presented typical 'incomplete tubular acidosis'. While glomerular function appears to present no special problems in renal transplant, tubular function displays anomalous patterns even over long periods. These cannot be readily ascribed to a definite cause, since there are a number of possible immunological, ischemic or therapeutic negative factors. In the absence of rejection lesions, however, the results may be considered as satisfactory even a short time after the operation.
|Number of pages||7|
|Publication status||Published - 1973|
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