Aspergillus galactomannan antigen in the cerebrospinal fluid of bone marrow transplant recipients with probable cerebral aspergillosis

Claudio Viscoli, Marco Machetti, Paola Gazzola, Andrea De Maria, Dimitri Paola, Maria Teresa Van Lint, Francesca Gualandi, Mauro Truini, Andrea Bacigalupo

Research output: Contribution to journalArticle

Abstract

The Aspergillus galactomannan test was performed on cerebrospinal fluid and serum samples from 5 patients with probable cerebral aspergillosis and from 16 control patients. Cerebrospinal fluid galactomannan levels were significantly higher in aspergillosis patients, and most galactomannan was produced intrathecally. Comparison of serum galactomannan values in pulmonary and cerebral aspergillosis patients showed significant overlapping. Detection of Aspergillus galactomannan in cerebrospinal fluid may be diagnostic of cerebral aspergillosis.

Original languageEnglish
Pages (from-to)1496-1499
Number of pages4
JournalJournal of Clinical Microbiology
Volume40
Issue number4
DOIs
Publication statusPublished - 2002

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ASJC Scopus subject areas

  • Microbiology (medical)
  • Microbiology

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