Aspetti epidemiologici, diagnostici e terapeutici nelle infezioni genitali da Human Papilloma Virus (HPV): Valutazione di un gruppo di 67 donne e di 34 partner maschili

The aim of our study is to analyze the incidence of Human Papilloma Virus (HPV) genital infection and to evaluate its diagnostic and therapeutic approach in 67 young women and their 34 partners at the 3rd Obstetrics and Gynecology Department of the Second University of Neaples. All patients and their partners were studied by clinical evaluation, cytology, colposcopy (or peniscopy) and eventually biopsy for histologic exam. Cytology showed that 49,25% of women were affected by LGSIL Lox grade squamous intraepithelial lesions) and 8,95% by HGSIL (High grade squamous intraepithelial lesions); 9,68%) of partners were affected by LGSIL and 3,22%) by HGSlL. Histology confirmed the diagnosis of LGSIL in 44,77% of women and in 6,45% of partners and of HGSIL in 8,95% of women and 3,22% of men. Comparison between cytologic and histologic evaluations revealed that cytology overrated LGSIL; all cytologic HIGSIL were confirmed by histology. Patients affected by genital HPV infection confirmed by histology have been treated with medical-physical therapy (Diathermocoagulation-Interferon); only 3 atients (4,48%) recurred to a second cycle of therapy for recurrence. The Authors conclude that the couple screening for genital HPV infections improves the therapy efficacy and it is helpful in the follow-up of such patients.