Aspirin underuse, non-compliance or cessation: Definition, extent, impact and potential solutions in the primary and secondary prevention of cardiovascular disease

Giuseppe Biondi-Zoccai, Yangfeng Wu, Carlos V. Serrano, Giacomo Frati, Pierfrancesco Agostoni, Antonio Abbate

Research output: Contribution to journalArticle

Abstract

Despite momentous breakthroughs in unraveling the pathophysiology of many chronic conditions and developing novel therapeutic agents, everyday clinical practice is still fraught with inadequate or inappropriate use of treatments with proven benefits. Aspirin is a paradigmatic example, as it is used for the primary and secondary prevention of cardiovascular disease and appears to have a beneficial impact on cancer risk. Yet, underuse, non-compliance or cessation of aspirin are not uncommon, may have an important clinical impact, and are not aggressively prevented or managed. Increasing the awareness of the extent and impact of aspirin underuse, non-compliance or cessation, and intensifying efforts at preventing them are worthy goals likely to yield significant benefits on cardiovascular morbidity and mortality worldwide, and possibly also on cancer outcomes.

Original languageEnglish
Pages (from-to)148-154
Number of pages7
JournalInternational Journal of Cardiology
Volume182
Issue numberC
DOIs
Publication statusPublished - 2015

Keywords

  • Aspirin
  • Cardiovascular disease
  • Cessation
  • Compliance
  • Discontinuation
  • Underuse

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Medicine(all)

Fingerprint Dive into the research topics of 'Aspirin underuse, non-compliance or cessation: Definition, extent, impact and potential solutions in the primary and secondary prevention of cardiovascular disease'. Together they form a unique fingerprint.

  • Cite this