Assay of estrogen and progesterone receptors in small samples of breast cancer: II. The conventional procedure compared to the mathematical one.

C. Viticchi, A. Basso, L. Piantanelli, A. Zaia

Research output: Contribution to journalArticle

Abstract

Parallel assays of ER and PR receptors have been performed in the same tissue samples using both the conventional method employing two sets of test tubes and a mathematical method which does not need the second set of tubes containing excess cold ligand concentrations. Determinations have been performed in calf uterus and human breast cancer samples. Findings show that the two methods give quite similar results. In particular, they are very close in human BC tissues where receptor density values show a very wide range. The mathematical method seems quite useful when the samples are poor of receptors, a case where the precision of the method may influence both prognosis and therapy.

Original languageEnglish
Pages (from-to)229-234
Number of pages6
JournalBollettino della Societa Italiana di Biologia Sperimentale
Volume70
Issue number8-9
Publication statusPublished - Aug 1994

ASJC Scopus subject areas

  • Medicine(all)

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