Parallel assays of ER and PR receptors have been performed in the same tissue samples using both the conventional method employing two sets of test tubes and a mathematical method which does not need the second set of tubes containing excess cold ligand concentrations. Determinations have been performed in calf uterus and human breast cancer samples. Findings show that the two methods give quite similar results. In particular, they are very close in human BC tissues where receptor density values show a very wide range. The mathematical method seems quite useful when the samples are poor of receptors, a case where the precision of the method may influence both prognosis and therapy.
|Number of pages||6|
|Journal||Bollettino della Societa Italiana di Biologia Sperimentale|
|Publication status||Published - Aug 1994|
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