Assessing of sympathovagal balance in patients with and without history of chronic heart failure

S. Scalvini, M. Volterrani, E. Zanelli, M. Campana, M. Pagani, A. Giordano

Research output: Contribution to journalArticlepeer-review


Purpose: Chronic heart failure (CHF) is associated with abnormal autonomie control of the cardiovascular system, such as decreased heart rate variability (HRV). Aim of this study is to compare the different behaviour of HRV in patients (pts) with left ventricular dysfunction with and without history of CHF. Methods: Fifty pts (mean age 60±10) with left ventricular dysfunction (EF 30±9%, range 14-40), following ischemic heart disease and with stable therapy for almost three months were studied. The pts were divided into two groups: Group 1 (30 pts) with history of CHF (15 pts with NYHA I-II and 15 with NYHA III-IV); Group 2 (20 pts) without history of CHF. All the pts underwent 2D-echo doppler and 24-Holter monitoring. HRV was evaluated through the autoregressive spectral analysis with 600 beat ECG samples, while the subjects were 1-quietly recumbent (BS1), 2-with controlled breathing (15 acts/min) (RSC), 3-passive orthostatism after tilting (80%) (TLT), both the time and frequency domain. Results: The low-frequency component (LF) in the basal condition was undetectable in 11 pts of the G1 and in 2 pts of G2 (p<0.008). ON the contrary G1 pts presented an increased in the high frequency normalized unit component (HF) in comparison of the G2 pts (57±4 vs 34±5) (p

Original languageEnglish
Issue number4 SUPPL.
Publication statusPublished - Oct 1996

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine


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