Assessing prognosis and optimizing treatment in patients with postchemotherapy viable nonseminomatous germ-cell tumors (NSGCT): Results of the sCR2 international study

K. Fizazi, J. Oldenburg, A. Dunant, I. Chen, R. Salvioni, J. T. Hartmann, M. De Santis, G. Daugaard, A. Flechon, U. De Giorgi, S. Tjulandin, H. J. Schmoll, J. Bouzy, S. D. Fossa, G. Fromont

Research output: Contribution to journalArticle

Abstract

Background: The purpose of this study was to validate a prognostic index [surgical complete response 1 (sCR1)] in patients with postchemotherapy viable nonseminomatous germ-cell tumors (NSGCT). Patients and methods: Data and specimens from 61 patients with normalized tumor markers and postchemotherapy viable nonteratomatous NSGCT treated in 13 institutions were collected. Results: With a median follow-up of 5.4 years, the 5-year progression-free survival (PFS) rate was 65%; the 5-year overall survival (OS) rate was 72%. Favorable PFS was predicted by a complete resection,

Original languageEnglish
Pages (from-to)259-264
Number of pages6
JournalAnnals of Oncology
Volume19
Issue number2
DOIs
Publication statusPublished - Feb 2008

Keywords

  • Chemotherapy
  • Germ cell tumor
  • Non seminoma
  • Residual masses
  • Surgery

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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    Fizazi, K., Oldenburg, J., Dunant, A., Chen, I., Salvioni, R., Hartmann, J. T., De Santis, M., Daugaard, G., Flechon, A., De Giorgi, U., Tjulandin, S., Schmoll, H. J., Bouzy, J., Fossa, S. D., & Fromont, G. (2008). Assessing prognosis and optimizing treatment in patients with postchemotherapy viable nonseminomatous germ-cell tumors (NSGCT): Results of the sCR2 international study. Annals of Oncology, 19(2), 259-264. https://doi.org/10.1093/annonc/mdm472