TY - JOUR
T1 - Assessment, diagnosisand treatment of Human Immunodeficiency Virus (HIV)-associated neurocognitive disorders (HAND)
T2 - A consensus report of the mind exchange program
AU - Antinori, Andrea
AU - Arendt, Gabriele
AU - Grant, Igor
AU - Letendre, Scott
AU - Muñoz-Moreno, Jose A.
PY - 2013/4/1
Y1 - 2013/4/1
N2 - Many practical clinical questions regarding the management of HAND remain unanswered. We sought to identify and develop practical answers to key clinical questions in HAND management. Sixty-six specialists from 30 countries provided input into the program, which was overseen by a steering committee. Fourteen questions were rated as being of greatest clinical importance. Answers were drafted by an expert group based on a comprehensive literature review. Sixty-three experts convened to determine consensus and level of evidence for the answers. Consensus was reached on all answers. For instance, good practice suggests that all HIV patients should be screened for HAND early in disease using standardized tools. Follow-up frequency depends on whether HAND is already present or whether clinical data suggest risk for developing HAND. Worsening neurocognitive impairment may trigger consideration of antiretroviral modification when other causes of have been excluded. The Mind Exchange program provides practical guidance in the diagnosis, monitoring and treatment of HAND.
AB - Many practical clinical questions regarding the management of HAND remain unanswered. We sought to identify and develop practical answers to key clinical questions in HAND management. Sixty-six specialists from 30 countries provided input into the program, which was overseen by a steering committee. Fourteen questions were rated as being of greatest clinical importance. Answers were drafted by an expert group based on a comprehensive literature review. Sixty-three experts convened to determine consensus and level of evidence for the answers. Consensus was reached on all answers. For instance, good practice suggests that all HIV patients should be screened for HAND early in disease using standardized tools. Follow-up frequency depends on whether HAND is already present or whether clinical data suggest risk for developing HAND. Worsening neurocognitive impairment may trigger consideration of antiretroviral modification when other causes of have been excluded. The Mind Exchange program provides practical guidance in the diagnosis, monitoring and treatment of HAND.
UR - http://www.scopus.com/inward/record.url?scp=84875042141&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84875042141&partnerID=8YFLogxK
U2 - 10.1093/cid/cis975
DO - 10.1093/cid/cis975
M3 - Article
C2 - 23175555
VL - 56
SP - 1004
EP - 1017
JO - Clinical Infectious Diseases
JF - Clinical Infectious Diseases
SN - 1058-4838
IS - 7
ER -