Assessment of atrial diastolic function in patients with hypertrophic cardiomyopathy by cine magnetic resonance imaging

Emanuele Grassedonio, Giancarlo Todiere, Ludovico La Grutta, Patrizia Toia, Giovanni D. Gentile, Massimo Galia, Federico Midiri, Alessia Pepe, Massimo Midiri, Giovanni Donato Aquaro

Research output: Contribution to journalArticle

Abstract

Purpose: This study was conducted to assess the role of atrial function by cardiac magnetic resonance (CMR) for the evaluation of diastolic physiology in patients with hypertrophic cardiomyopathy (HCM) compared to healthy controls. Materials and methods: We enrolled 23 consecutive patients affected by HCM and 43 healthy subjects as age-matched control cases (CC). CMR was performed through acquisition of cine steady-state free precession sequences using a 1.5-T scanner. Image postprocessing was carried out using Tracking Tool software. Results: Atrial volumes were significantly higher in patients with HCM compared to CC: maximum atrial volume (p = 0.007) and minimum atrial volume (p = 0.01). A statistically significant difference was also observed in atrial ejection fraction in patients with HCM (p 

Original languageEnglish
Pages (from-to)714-722
Number of pages9
JournalRadiologia Medica
Volume120
Issue number8
DOIs
Publication statusPublished - Aug 24 2015

Keywords

  • Atrial function
  • Cardiac magnetic resonance
  • Diastolic function
  • Hypertrophic cardiomyopathy

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Medicine(all)

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    Grassedonio, E., Todiere, G., La Grutta, L., Toia, P., Gentile, G. D., Galia, M., Midiri, F., Pepe, A., Midiri, M., & Aquaro, G. D. (2015). Assessment of atrial diastolic function in patients with hypertrophic cardiomyopathy by cine magnetic resonance imaging. Radiologia Medica, 120(8), 714-722. https://doi.org/10.1007/s11547-015-0497-1