Assessment of bone architecture with ultrasonometry: Experimental and clinical experience

Ruggero Cadossi, Francesca De Terlizzi, Valerio Canè, Milena Fini, Christian Wüster

Research output: Contribution to journalArticlepeer-review


Over the last decade, ultrasound technology has been introduced as a method of analysing bone tissue in clinical practice, and several studies have compared various ultrasound devices with dual-energy X-ray absorptiometry (DXA). Unlike DXA, the ultrasound technique is not limited to the measurement of bone density - it also has the potential to provide information on the mechanical and architectural characteristics of bone. The first generation of ultrasound devices used the speed of sound and attenuation of the ultrasound signal to obtain information on bone mineral content. Second generation ultrasound devices, which analyse the ultrasound signal received, permit the study of bone structure and elasticity, in addition to its mineral content, in both experimental studies and clinical practice. This is accomplished by signal processing analysis, the study of backscattering and the application of Biot's theory. This approach to the study of bone tissue represents the future for the development of ultrasound technology for use in clinical practice.

Original languageEnglish
Pages (from-to)9-18
Number of pages10
JournalHormone Research
Issue numberSUPPL. 1
Publication statusPublished - 2000


  • Bone
  • Osteoporosis
  • Ultrasonics
  • Ultrasonometry

ASJC Scopus subject areas

  • Endocrinology


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